标题：七氟醚吸入辅助硬膜外阻滞用于剖宫产对新生儿Apgar评分的影响

      作者：周晓筠 1，王祥云 2*
    (1.中山市博爱医院麻醉科，广东 中山 528403；
2.东莞市石龙人民医院，广东 东莞 523326)

      卷次： 2012年23卷1期

      【摘要】 目的 比较七氟醚吸入辅助硬膜外阻滞麻醉与单纯硬膜外阻滞麻醉用于剖宫产术对新生儿Apgar
评分的影响，探讨七氟醚用于产科麻醉的可行性。方法 选取择期剖宫产的足月初产妇80例，随机分为两组：七
氟醚吸入辅助硬膜外阻滞麻醉组(实验组，n=40)；单纯硬膜外阻滞麻醉组(对照组，n=40)。两组均于L2~3或L3~4行
硬膜外穿刺，予2%利多卡因15~20 ml维持麻醉，实验组于切皮前面罩吸入七氟醚6%~8%至产妇意识完全消失，
再以1.5%~2.5%的浓度维持至胎儿娩出；对照组不加任何辅助药物，记录两组产妇的ECG、BP、SpO2等生命体征、
产妇吸入七氟醚至胎儿娩出的时间以及胎儿娩出后1 min、5 min、10 min的Apgar评分。结果 吸入七氟醚至胎
儿娩出的时间两组均在5~10 min，两组新生儿Apgar评分差异无统计学意义(P>0.05)，实验组有3例新生儿Apgar
评分≤7分(7.5%)；对照组有2例(5.0%)，经吸氧简单处理后5 min的Apgar评分均为10分。结论 七氟醚吸入辅
助硬膜外阻滞麻醉用于剖宫产对新生儿Apgar评分无明显影响。

      【关键词】 七氟醚；连续硬膜外阻滞；剖宫产；Apgar评分

      【中图分类号】 R719.8 【文献标识码】 A 【文章编号】 1003—6350（2012）01—044—03<

br>Effect of epidural block anesthesia adjuvanted with seroflurane inhalation in caesarean section on Apgar scores
of newborn.
ZHOU Xiao-jun 1, WANG Xiang-yun 2. 1. Department of Anesthesiology, Bo'ai Hospital of Zhongshan City,
Zhongshan 52840, Guangdong, CHINA; 2. Shilong People's Hospital of Dongguan City, Dongguan 523326, Guangdong,
CHINA

【Abstract】 Objective To compare the effect of epidural block anesthesia adjuvanted with seroflurane inhala-
tion and epidural block anesthesia on Apgar scores of newborns after Caesarean section, to discuss the feasibility of us-
ing sevoflurane in obstetrical anesthesia. Methods Eighty cases of full term primipara were randomly and equally di-
vided into two groups: the study group (treated by epidural block anesthesia adjuvanted with seroflurane inhalation)
and the control group (treated by epidural block anesthesia singly). Patients in the two groups were both punctured in
L2~3 or L3~4 with epidural injection of 15~20 ml 2% lidocaine. Patients in the study group inhaled 1.5%~2.5% sevoflu-
rane till the fetus was delivered. The vital signs, ECG, BP, SpO2, the time from drug administration to the delivery and
Apgar scores at 1 min, 5 min and 10 min after the delivery were recorded. Results The time from drug administra-
tion to the delivery in the two groups were both 5~10 minutes. Apgar scores showed no statistically significant differ-
ence between the two groups (P>0.05). 3 cases (7.5%) in the study group and 2 cases (5.0%) in the control group were
found with Apgar scores≤7. Apgar scores reached 10 after treated with oxygen inhalation. Conclusion Adjuvant
use of sevoflurane inhalation exerts no obvious effect on Apgar scores of newborn after caesarean section.

      【Key words】 Sevoflurane; Epidural block anesthesia; Caesarean section; Apgar score
作者简介：周晓筠(1976—)，女，广东省中山市人，主治医师，本科。
*通讯作者：王祥云，主任医师。E-mail：20080808.bjhyn@163.com
·临床研究·