标题：妊娠合并乙型肝炎病毒感染对妊娠结局的影响

      作者：周玉华
    (三亚市人民医院妇产科，海南 三亚 572000)

      卷次： 2012年23卷1期

      【摘要】 目的 探讨妊娠合并乙型肝炎病毒感染及无症状乙型肝炎病毒携带状态对妊娠结局的影响。
方法 将 173例在我院住院分娩的妊娠合并HBV感染者患者分为两组：无症状乙肝病毒携带者 82例(无症状
组)、肝功能受损者 91例(乙肝组)。随机选择同期 90例正常产妇作为对照组，对围生期结局进行回顾性分析比
较。 结果 乙肝组早产、妊高征、胎儿窘迫、新生儿窒息、产后出血的发生率最高，依次是 14.29%，27.47%，
39.56%，24.18%，23.08%，无症状组相应为 3.66%，12.20%，20.73%，8.54%，9.76%，对照组相应为 1.11%，3.33%，
17.78%，6.67%，4.44%，乙肝组与另两组比较差异有统计学意义(P< 0.01)。结论 妊娠合并乙型肝炎病毒感染与
早产、妊高征、胎儿窘迫、新生儿窒息、产后出血等不良妊娠结局有关，应重视产前检查及孕期肝功能检测，尽早
采取预防及治疗措施。

      【关键词】 妊娠；乙型肝炎病毒；妊娠结局

      【中图分类号】 R714.251 【文献标识码】 A 【文章编号】 1003—6350（2012）01—040—02<

br>Effect of hepatitis B virus infection during pregnancy on the pregnancy outcome.
ZHOU Yu-hua. Department of
Obstetrics and Gynaecology, People's Hospital of Sanya City, Sanya 572000, Hainan, CHINA

【Abstract】 Objective To investigate the effect of hepatitis B virus infection during pregnancy on the preg-
nancy outcome. Methods A retrospective study was conducted on the perinatal outcome of 173 cases of hepatitis B
virus infection during pregnancy and 90 cases of normal pregnancy (the control group. The 173 patients were divided
into two groups: group A (Hepatitis B virus carriers without symptoms) and group B (Hepatitis B virus carriers with
impaired liver function). Results The incidence of premature delivery, pregnancy-induced hypertension syndrome,
fetal distress, newborn asphyxia and postpartum hemorrhage in group B were 14.29% , 27.47% , 39.56% , 24.18% ,
23.08%, respectively, significantly higher than the other two groups (P<0.01). Conclusion Hepatitis B infection dur-
ing pregnancy can affect the pregnancy outcome significantly, thus prenatal examination and liver function test during
pregnancy should be emphasized.

      【Key words】 Pregnancy; Hepatitis B virus; Pregnancy outcome
作者简介:周玉华（1972—），女，海南省三亚市人，主治医师，学士，主要从事临床医学工作。
·临床研究·