标题：继发性甲状旁腺亢进对心血管系统的影响及其治疗进展

      作者：蔡宝乐，施辉    (南通大学附属医院肾内科，江苏 南通 226000)

      卷次： 2018年29卷13期

      【摘要】 继发性甲状旁腺功能亢进(SHPT)是慢性肾脏疾病的常见并发症，由钙、磷酸盐和维生素D平衡紊乱引起的甲状旁腺升高疾病。甲状旁腺激素(PTH)升高的慢性肾病患者其心血管疾病和骨骼疾病的发生率显著增加。目前采用钙受体激动剂、铁磷结合剂、维生素D制剂及甲状旁腺切除术来缓解SHPT，本文就SPTH对心血管病的影响及其治疗措施的研究进展做一综述。
      【关键词】 继发性甲状旁腺功能亢进；慢腺性肾脏疾病；心血管病；治疗
      【中图分类号】 R582+.1 【文献标识码】 A 【文章编号】 1003—6350（2018）13—1857—04

Effect of secondary hyperparathyroidism on cardiovascular system and its treatment progress.
CAI Bao-le, SHIHui. Department of Nephrology, the Affiliated Hospital of Nantong University, Nantong 226000, Jiangsu, CHINA【Abstract】 Secondary hyperparathyroidism (SHPT), a common complication of chronic kidney disease (CKD),is characterized by elevated parathyroid hormone levels caused by derangements in the homeostasis of calcium, phos-phate, and vitamin D. Chronic kidney patients with high parathyroid hormne (PTH) have increased incidence of cardio-vascular disease and bone disease. At present, calcimimetic drugs, phosphate binders, vitamin D analogs, and parathy-roidectomy can be used to relieve SHPT. In this paper, the impact of SPTH on cardiovascular disease and its treatmentmeasures were reviewed.
      【Key words】 Secondary hyperparathyroidism (SHPT); Chronic kidney disease (CKD); Cardiovascular disease;Treatment·综 述·doi:10.3969/j.issn.1003-6350.2018.13.025