标题：冠脉慢性完全闭塞病变临床治疗的研究进展

      作者：石英明 1，田镭钢 2，饶绍奇 3，梁岩 2    (1.广东医科大学研究生院，广东 湛江 524023；2.茂名市人民医院心内科，广东 茂名 525000；3.广东医科大学医学系统生物学研究所与公共卫生学院，广东 东莞 523808)

      卷次： 2018年29卷13期

      【摘要】 冠状动脉慢性完全闭塞病变(CTO)在冠心病中较为常见，近年来，CTO的研究已成为热点之一，尤以研究其治疗方法为多。成功的治疗可以改善心室功能，缓解患者的临床症状，提高患者的生活质量，改善预后。随着患者对CTO的重视，医生治疗理念的发展及治疗技术的进步，冠状动脉慢性完全闭塞病变的治疗取得了明显的进展。
      【关键词】 冠状动脉粥样硬化性心脏病；慢性完全闭塞；治疗；研究进展
      【中图分类号】 R543.3 【文献标识码】 A 【文章编号】 1003—6350（2018）13—1854—04

Progress in the clinical treatment of coronary chronic total occlusion lesions.
SHI Ying-ming 1, TIAN Lei-gang 2,RAO Shao-qi 3, LIANG-Yan 2. 1. Graduate School, Guangdong Medical University, Zhanjiang 524023, Guangdong, CHINA;2. Department of Cardiology, Maoming People's Hospital, Maoming 525000, Guangdong, CHINA; 3. Institute of MedicalSystems Biology and School of Public Health, Guangdong Medical University, Dongguan 523808, Guangdong, CHINA【Abstract】 Chronic total occlusion (CTO) of coronary arteries is more common in coronary heart disease(CHD). In recent years, CTO research has become one of the hot spots, especially in the study of its treatment methods.Successful treatment can improve ventricular function, ease the patient's clinical symptoms, improve their quality of lifeand prognosis. With the patient's attention to the CTO, the development of the doctor's treatment concept and the prog-ress of the treatment technology, the treatment of chronic total occlusion of coronary artery has been significantly im-proved.
      【Key words】 Coronary heart disease (CHD); Chronic total occlusion (CTO); Therapy; Research progress·综 述·doi:10.3969/j.issn.1003-6350.2018.13.024基金项目：国家自然科学基金(编号：31071166/81373085)；广东省科技计划攻关项目(编号：2009A030301004)；广东省东莞市科技重点项目(编号：201108101015)；广东医学院基金(编号：XG1001、JB1214、XZ1105、STIF201122)