标题：年龄相关性黄斑变性流行病学研究进展

      作者：李之忠    (天津海滨人民医院眼科，天津 300280)

      卷次： 2018年29卷11期

      【摘要】 年龄相关性黄斑变性在临床中属于一种与年龄相关的致盲性退行性眼底病变，随着人们老龄化的加剧，黄斑变性的发病率呈现逐年增长的趋势。现阶段年龄相关性黄斑变性发病机制尚未完全明确，主要认为与炎症免疫反应及氧化应激等因素相关，临床中主要针对患者实施药物治疗、激光光凝治疗、光动力治疗、放射治疗、经瞳孔温热治疗、中医治疗、剥离体腔注射拮抗剂、黄斑下手术等方式。本文主要针对年龄相关性变性患者的具体情况及引起流行病学因素进行了相应的分析。
      【关键词】 年龄相关性；黄斑变性流行病学；研究；进展
      【中图分类号】 R774.5 【文献标识码】 A 【文章编号】 1003—6350（2018）11—1574—03

Progress in epidemiologic study of age-related macular degeneration.
LI Zhi-zhong. Department of Ophthalmology,Tianjin Haibin People's Hospital, Tianjin 300280, CHINA【Abstract】 Age-related macular degeneration (AMD) is a kind of age-related blindness degenerative fundus le-sions in clinic. As the aging of the population intensified, the incidence of macular degeneration is increasing year by year.At present, the pathogenesis of AMD is not fully clear, and it is reported that it may be related to inflammatory immune re-sponse and oxidative stress. Clinical treatments mainly include drug therapy, laser photocoagulation operation, radiationtherapy, the pupil warm treatments, Chinese medicine treatment, intravitreous injection of antagonist, submacular surgery.This paper mainly presents the specific situation of patients with AMD and progress in the epidemiological studies.
      【Key words】 Age-related; Epidemiology of macular degeneration; Research; Progress·综 述·doi:10.3969/j.issn.1003-6350.2018.11.028