标题:类风湿关节炎与高脂饮食、肠道菌群的关系研究进展
作者:梁量 1,周宇 2,梁坚 2 (广东医科大学附属医院风湿免疫科 1、消化内科 2,广东 湛江 524000)
卷次:
2018年29卷10期
【摘要】 类风湿关节炎是一种以慢性关节炎症为主要表现的全身自身免疫性疾病,其发病受众多因素的影响,有待进一步明确。许多研究发现,高脂饮食可能通过诱发肠道菌群失调,进而参与类风湿关节炎发病。本文仅对高脂饮食及肠道菌群失调与类风湿关节炎的发病关系进行相关综述,以期为类风湿性关节炎的防治提供新的策略。
【关键词】 高脂饮食;高脂血症;肥胖;肠道菌群;类风湿关节炎
【中图分类号】 R593.22 【文献标识码】 A 【文章编号】 1003—6350(2018)10—1427—03
Research progress on the relationship between rheumatoid arthritis and high-fat diet and intestinal microbiota.LIANG Liang 1, ZHOU Yu 2, LIANG Jian 2.
Department of Rheumatology 1, Department of Gastroenterology 2, the AffiliatedHospital of Guangdong Medical University, Zhanjiang 524000, Guangdong, CHINA【Abstract】 Rheumatoid arthritis is a systemic autoimmune disease characterized by chronic joint inflammation.Its incidence is affected by many factors, which need to be further clarified. Many studies have found that high-fat dietmay lead to the onset of rheumatoid arthritis by inducing intestinal dysbacteriosis. This article reviews the pathogenesisof high-fat diet and intestinal dysbacteriosis and rheumatoid arthritis, with a view to providing new strategies for the pre-vention and treatment of rheumatoid arthritis.
【Key words】 High-fat diet; Hyperlipemia; Obesity; Intestinal microbiota; Rheumatoid arthritis·综 述·doi:10.3969/j.issn.1003-6350.2018.10.029
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