标题：急性肾损伤的试验性标志物和评估

      作者：康福新，王小智    (海南医学院第二附属医院重症医学科，海南 海口 570311)

      卷次： 2018年29卷7期

      【摘要】 急性肾损伤(AKI)是危重患者常见的并发症之一，临床已经确定了多种生物标志物用于AKI的诊断，如中性粒细胞明胶酶相关脂质运载蛋白(NGAL)、尿损伤分子-1 (KIM-1)等。本文就临床中常用的诊断及预测重症AKI及其他不良结局的生物标志物做一概述。
      【关键词】 急性肾损伤；生物标志物；诊断；预测
      【中图分类号】 R692 【文献标识码】 A 【文章编号】 1003—6350（2018）07—0977—03

Biomarkers and evaluation of acute kidney injury.
KANG Fu-xin, WANG Xiao-zhi. Intensive Care Unit, the SecondAffiliated Hospital of Hainan Medical University, Haikou 570311, Hainan, CHINA【Abstract】 Acute kidney injury (AKI) is one of the most common complications of critically ill patients. A vari-ety of biomarkers have been identified for the diagnosis of AKI, such as neutrophil gelatinase-associated lipid transportprotein (NGAL) and urinary injury molecules-1 (KIM-1). This paper gives an overview of biomarkers commonly usedfor diagnosing and predicting severe AKI and other adverse outcomes.
      【Key words】 Acute kidney injury; Biomarker; Diagnosis; Predict·综 述·doi:10.3969/j.issn.1003-6350.2018.07.028基金项目：海南省自然科学基金(编号：20168294)