标题：气管瘢痕狭窄动物模型的研究进展

      作者：王志鹏，张春林，刘兆辉    遵义医科大学附属医院耳鼻咽喉头颈外科，贵州 遵义 563000

      卷次： 2019年30卷10期

      【摘要】 气管狭窄是气管切开严重的术后并发症，严重影响患者生存质量，临床处理棘手。气管狭窄的发病机制复杂，目前仍未完全清楚，本文将近年来学者关于气管狭窄的动物模型及发生机制的研究做一综述。
      【关键词】 气管狭窄；动物模型；机制；瘢痕；纤维化
      【中图分类号】 R653 【文献标识码】 A 【文章编号】 1003—6350（2019）10—1326—03

Advances in research on animal models of tracheal scar stenosis.
WANG Zhi-peng, ZHANG Chun-lin, LIU Zhao-hui.Department of Otorhinolaryngology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou, CHINA【Abstract】 Tracheal stenosis is a serious postoperative complication of tracheotomy, which seriously affects thequality of life of patients and is difficult to treat clinically. The pathogenesis of tracheal stenosis is complex and still notfully understood. This article reviews recent studies on animal models and mechanisms of tracheal stenosis.
      【Key words】 Tracheal stenosis; Animal model; Mechanism; Scar; Fibrosis·综述·doi:10.3969/j.issn.1003-6350.2019.10.030基金项目：国家自然科学基金(编号：81760493、81860482)