首页 > 期刊检索 > 详细
      标题:亲水性银离子敷料与磺胺嘧啶银治疗深Ⅱ度烧伤疗效观察
      作者:刘薇,程红霞,蒋紫玟    (十堰市太和医院湖北医药学院附属医院整形烧伤美容科,湖北 十堰 442000)
      卷次: 2018年29卷1期
      【摘要】 目的 比较亲水性银离子敷料与磺胺嘧啶银治疗深Ⅱ度烧伤患者的临床疗效。方法 选择2014年4月至2016年4月十堰市太和医院接诊的80例深Ⅱ度烧伤患者,按随机数表法分为观察组和对照组各 40例。对照组在创面均匀涂抹 1%磺胺嘧啶银霜乳膏,换药频率 1次/d,观察组给予亲水性银离子敷料,根据创面形状修剪辅料大小,加以纱布包扎,换药频率 3~5 d/次。比较两组患者创面愈合情况及血清炎症因子变化。结果 观察组患者创面愈合时间为(17.58±2.48) d,短于对照组的(22.13±3.42) d,换药次数为(5.02±0.79)次,少于对照组的(7.34±0.84)次,差异均有统计学意义(P<0.05);观察组患者在7 d、14 d、21 d时创面愈合率分别为(60.23±4.78)%、(82.35±5.14)%、(93.42±2.03)%,均高于对照组的(51.32±5.09)%、(74.23±5.17)%、(88.45±3.49)%,差异均具有统计学意义(P<0.05);观察组治疗后白介素-6 (IL-6)、肿瘤坏死因子α (TNF-α)水平为(0.43±0.07) pg/mL、(0.63±0.12) pg/mL,均低于对照组的(0.54±0.08) pg/mL、(0.76±0.11) pg/mL,差异均有统计学意义(P<0.05);两组患者创面分泌物细菌检出阳性率比较差异无统计学意义(P>0.05)。结论 亲水性银离子敷料治疗深Ⅱ度烧伤可有效降低患者的炎症因子水平,促进创面愈合,临床治疗效果显著。
      【关键词】 烧伤;银离子敷料;磺胺嘧啶银;创面愈合;炎症因子
      【中图分类号】 R644 【文献标识码】 A 【文章编号】 1003—6350(2018)01—0056—03
Clinical efficacy of hydrophilic silver ion dressing and silver sulfadiazine in the treatment of deep partialthickness burns. LIU Wei, CHEN Hong-xia, JIANG Zi-wen. Department of Plastic Surgery, Shiyan Taihe hospital (theAffiliated Hospital of Hubei Medical College), Shiyan 442000, Hubei, CHINA
      【Abstract】 Objective To analyze the clinical efficacy of hydrophilic silver ion dressing and silver sulfadiazinein the treatment of deep partial thickness (second-degree) burns. Methods Eighty patients with deep partial thicknessburns in our hospital from April 2014 to April 2016 were selected and divided randomly into observation and controlgroups, each with 40 cases. The control group applied 1% sulfadiazine silver cream evenly on wound surface, with dress-ing frequency of 1 time/d. The observation group were treated with hydrophilic silver ion dressing, trim the size of thematerial according to the shape of the wound, with dressing frequency of 3~5 d/time. They two groups were compared inwound healing, the changes of serum inflammatory factors and adverse reaction. Results The healing time, number ofdressing change were (17.58±2.48) d, (5.02±0.79) in the observation group versus (22.13±3.42) d, (7.34±0.84) in the con-trol group (P<0.05). The wound healing rate at 7 d, 14 d, 21 d were (60.23±4.78)%, (82.35±5.14)%, (93.42±2.03)% inthe observation group, which were significantly higher than (51.32±5.09)%, (74.23±5.17)%, (88.45±3.49)% in the con-trol group (P<0.05). After treatment, the levels of interleukin-6 (IL-6), tumor necrosis factor α (TNF-α) were (0.43±0.07) pg/mL, (0.63 ± 0.12) pg/mL in the observation group, which were significantly lower than (0.54 ± 0.08) pg/mL,(0.76±0.11) pg/mL in the control group (P<0.05). There was no significant difference between the two groups in the posi-tive rate of bacterial secretion (P>0.05). Conclusion The effect of hydrophilic silver ion dressing in the treatment ofdeep partial thickness burns patients is more significant than that of silver sulfadiazine, which can effectively reduce thelevel of inflammatory factors and can help to promote wound healing.
      【Key words】 Burns; Silver ion dressing; Silver sulfadiazine; Wound healing; Inflammatory factors·论 著·doi:10.3969/j.issn.1003-6350.2018.01.017
      基金项目:湖北省自然科学基金(编号:2015FFB04312)

       下载PDF