标题：彩色多普勒超声检查对慢性乙型肝炎肝纤维化的诊断价值

      作者：杨敬恩，李若攀，梁清    (贵港市第二人民医院功能科，广西 贵港 537132)

      卷次： 2017年28卷8期

      【摘要】 目的 探讨彩色多普勒超声在慢性乙型肝炎肝纤维化诊断中的应用价值。方法 选取2012年3月至2015年4月期间贵港市第二人民医院收治的256例慢性乙型肝炎患者，根据肝纤维化病理诊断结果分为S0期(48例)、S1期(52例)、S2期(50例)、S3期(64例)、S4期(42例)，同时选取46例健康体检人员作为对照组，均接受彩色多普勒超声检查，对比各组检查结果。结果 门静脉内径(Dpv)及肝固有动脉峰值血流速度(HAVmax)随肝脏纤维化的加重而明显增高(P<0.05)，门静脉峰值血流速度(PVVmax)随肝脏纤维化的加重而明显降低(P<0.05)；不同肝脏纤维化分期之间脾动脉搏动指数(SPPI)比较差异无统计学意义(P>0.05)，肝固有动脉血流峰值与门静脉血流峰值比(A/P)随肝脏纤维化的加重而明显增高(P<0.05)，肝循环指数(HCI)随肝脏纤维化的加重而明显降低(P<0.05)；S3、S4期肝静脉频谱异常率与对照组、S0、S1期比较差异均有统计学意义(P<0.05)。结论 彩色多普勒超声用于慢性乙型肝炎肝脏纤维化的诊断及分期将具有重要临床价值。
      【关键词】彩色多普勒超声；慢性乙型肝炎；肝纤维化；诊断
      【中图分类号】 R512.6+2 【文献标识码】 A 【文章编号】 1003—6350（2017）08—1293—03

Application of color Doppler ultrasound in the diagnosis of liver fibrosis of chronic hepatitis B.
YANG Jing-en, LIRuo-pan, LIANG Qing. Functional Department, Guigang Second People's Hospital, Guigang 537132, Guangxi, CHINA
【Abstract】 Objective To discuss the clinical value of color Doppler ultrasound in the diagnosis of liver fibro-sis of chronic hepatitis B. Methods A total of 256 patients with chronic hepatitis B from Guigang Second People's Hos-pital from March 2012 to April 2015 were divided into five stages according to pathological results: S0 (n=48), S1 (n=52),S2 (n=50), S3 (n=64), S4 (n=42). During the same period, 46 healthy people were divided into the control group. Then col-or Doppler ultrasound was performed in the subjects, and the results were contrasted. Results With the increase of the de-gree of liver fibrosis diameter of portal vein (Dpv), hepatic artery maximal velocity (HAVmax), and the ratio of HAVmax toportal venous maximum velocity (A/P) were significantly increased (P<0.05), while portal venous maximum velocity(PVVmax) and hepatic circulation index (HCI) were significantly reduced (P<0.05). There was no significant difference insplenic artery pulsatility index (SPPI) between different degrees of liver fibrosis (P>0.05). Abnormal rate of hepatic ve-nous spectrum in S3, S4 was significantly higher than that in the control group, S0, S1 (P<0.05). Conclusion Color Dop-pler ultrasound has important significance in the diagnosis of liver fibrosis of chronic hepatitis B.
      【Key words】 Color Doppler ultrasound; Chronic hepatitis B; Liver fibrosis; Diagnosis·论 著·doi:10.3969/j.issn.1003-6350.2017.08.031