标题：益气活血法治疗缺血性脑卒中的疗效及其对患者颈动脉粥样硬化斑块的影响

      作者：任胜洪，柯绍兴，石燕芳，张瑞娟，郭艳    (重庆市九龙坡区中医院脑病科，重庆 400080)

      卷次： 2017年28卷9期

      【摘要】 目的 探讨益气活血法治疗缺血性脑卒中的疗效及其对患者颈动脉粥样硬化斑块的影响。方法 选择2015年1月至2016年7月期间我院脑病科收治的96例缺血性脑卒中患者为研究对象，根据随机数字表法随机分为两组，每组48例，对照组患者予阿司匹林、阿托伐他汀等常规治疗，观察组患者联合应用益气活血法治疗，疗程均为1个月。比较两组患者治疗前后的颈动脉内膜中层厚度(IMT)、斑块积分的变化以及临床疗效。结果 观察组与对照组患者治疗后的颈动脉 IMT及斑块积分分别为(1.09±0.19) mm、(3.26±0.32)分和(1.17±0.16) mm、(3.67±0.39)分，与治疗前的(1.29±0.33) mm、(3.91±0.41)分和(1.28±0.24) mm、(4.01±0.42)分比较均显著降低，且观察组低于对照组，差异均有统计学意义(P<0.05)；观察组患者的治疗总有效率为89.58%，明显高于对照组的72.92%，差异有统计学意义(P<0.05)。结论 在常规治疗基础上联合应用益气活血法治疗缺血性脑卒中患者，可有效稳定颈动脉粥样硬化斑块，提高临床疗效。
      【关键词】 缺血性脑卒中；益气活血法；动脉粥样硬化；斑块；疗效
      【中图分类号】 R743.3 【文献标识码】 A 【文章编号】 1003—6350（2017）09—1398—03

Effect of Yiqi Huoxue therapy on ischemic stroke and its effect on carotid atherosclerotic plaque.
SHEN Hong-ren,KE Shao-xing, SHI Yan-fang, ZHANG Rui-juan, GUO Yan. Department of Encephalopathy, Jiulongpo District Hospital ofTraditional Chinese Medicine, Chongqing 400080, CHINA
【Abstract】 Objective To investigate the therapeutic effect of Yiqi Huoxue therapy on ischemic stroke and itseffect on carotid atherosclerotic plaque. Methods A total of 96 patients with ischemic stroke, who admitted to Depart-ment of Encephalopathy of our hospital from October 2015 to July 2016 were selected and randomly divided into twogroups according to random number table method, with 48 cases in each group. The control group were treated with aspi-rin, atorvastatin and other conventional treatment, and the observation group was treated with Yiqihuoxue treatment com-bined with other conventional treatment. The course of treatment of the two groups was 1 month. Carotid intima-mediathickness (IMT), plaque score changes were compared before and after treatment, and the clinical efficacy were alsocompared. Results The IMT and plaque scores of the carotid artery in the observation group and the control group af-ter the treatment were (1.09±0.19) mm, (3.26±0.32) and (1.17±0.16) mm, (3.67±0.39), respectively, which were signifi-cantly lower than (1.29±0.33) mm, (3.91±0.41) and (1.28±0.24) mm, (4.01±0.42) in the two groups before treatment (P<0.05). The total effective rate in the observation group was 89.58%, which was significantly higher than 72.92% in thecontrol group (P<0.05). Conclusion In the patients with ischemic stroke, Yiqi Huoxue therapy combined with conven-tional treatment can effectively stabilize the atherosclerotic plaques and improve the clinical curative effect.
      【Key words】 Ischemic stroke; Yiqi Huoxue; Atherosclerosis; Plaque; Curative effect·论 著·doi:10.3969/j.issn.1003-6350.2017.09.007