标题：结肠直肠恶性肿瘤手术部位感染原因分析

      作者：何纪恩，李晓花
    (宝鸡市中心医院肿瘤外科，陕西 宝鸡 721006)

      卷次： 2016年27卷19期

      【摘要】 目的 分析结肠直肠恶性肿瘤术后手术部位感染的原因，为针对性的预防提供参考。方法 回顾性
分析我院2013年1月至2015年12月319例结肠直肠恶性肿瘤切除术后患者的临床资料，根据手术部位感染与否分
为感染组(30例)和非感染组(289例)，比较两组患者的性别、年龄、手术方式、美国麻醉师协会(ASA)评级、Dukes分
期等，以找出感染原因。结果 单因素分析结果显示，两组患者在开腹手术、年龄、手术时间、出血量、Dukes分期、
ASA分级、合并糖尿病、营养不良等方面比较差异均具有统计学意义(P<0.05)；多因素Logistic回归分析结果显示，年
龄、合并糖尿病、手术时间长、营养不良及ASA分级>Ⅲ级是结肠直肠恶性肿瘤患者手术部位感染的主要影响因素，而
腹腔镜手术是手术部位感染的保护因素。结论 高龄、手术时间长、合并糖尿病、营养不良及ASA分级>Ⅲ级是导致结
肠直肠恶性肿瘤术后感染的主要原因，因此围术期应加强以上感染因素的控制以降低手术部位感染率。

      【关键词】 结肠直肠恶性肿瘤；手术；手术部位感染；原因

      【中图分类号】 R735 【文献标识码】 A 【文章编号】 1003—6350（2016）19—3223—02


Cause analysis of surgical site infection in patients with colorectal malignant tumor.
HE Ji-en, LI Xiao-hua.
Department of Surgical Oncology, the Central Hospital of Baoji, Baoji 721006, Shaanxi, CHINA

【Abstract】 Objective To analyze the cause of surgical site infection in patients with colorectal malignant tu-
mor after operation, and to provide reference for corresponding prevention. Methods The clinical data of 319 pa-
tients with colorectal malignant tumor after resection in our hospital from January 2013 to December 2015 were retro-
spectively reviewed. According to whether there was surgical site infection, the patients were divided into infection
group (n=30) and the non-infection group (n=289). The gender, age, operation method, the American society of anes-
thesiologists (ASA) rating, Dukes staging of patients were compared between the two groups, and the reasons of the in-
fection were analyzed. Results Single factor analysis showed that laparotomy, age, operation time, blood loss, Dukes
staging, ASA classification, complicated with diabetes, malnutrition of patients showed statistically significant differenc-
es between the two groups (P<0.05). Multiariable logistic regression analysis showed that age, diabetes mellitus, long op-
eration time, malnutrition and ASA classification>grade Ⅲ were the main influence factors of surgical site infection in
patients with colorectal malignant tumor, and the laparoscopic surgery was protective factor for surgical site infection.
Conclusion Age, long operation time, complicated with diabetes, malnutrition and ASA classification>gradeⅢ are the
main causes of postoperative infection in patients with colorectal malignant tumor. Therefore, the perioperative above
factors of infection control should be strengthened in order to reduce surgical site infection.

      【Key words】 Colorectal malignant tumor; Operation; Surgical site infection; Cause
·临床经验·doi:10.3969/j.issn.1003-6350.2016.19.044