标题：静电纺丝纤维支架在软骨组织重建中的设计应用

      作者：王春晖，贺娇娇，王思涵，郭小凯，赵明璨，刘畅
    (吉林大学口腔医院正畸科，吉林 长春 130021)

      卷次： 2016年27卷19期

      【摘要】 软骨损伤是临床常见疾病之一。软骨是一种无神经和血管营养的组织，其自身修复能力很差。组织
工程学为解决这一难题提供了新方法。组织工程学主要由支架材料、种子细胞和生长因子三要素构成。而其中支
架材料是近年来组织工程学研究的热点。静电纺丝技术更是由于其能形成多孔隙的纳米纤维支架而备受青睐。
本文具体介绍静电纺丝技术在软骨组织工程学中的设计应用。

      【关键词】 组织工程；支架材料；静电纺丝；软骨

      【中图分类号】 R329.3 【文献标识码】 A 【文章编号】 1003—6350（2016）19—3197—03


Application of electrospinning technology in the cartilage tissue engineering.
WANG Chun-hui, HE Jiao-jiao, WANG
Si-han, GUO Xiao-kai, ZHAO Ming-can, LIU Chang. School of Stomatology, Jilin University, Changchun 130021, Jilin,
CHINA
【Abstract】 Cartilage injury is one of clinical common diseases. Since cartilage is a kind of tissue without nerves
and blood vessels, its self-repair ability is limited. Tissue engineering provides an approach to solve this problem. Tissue
engineering is mainly composed of scaffolds, seeding cells and growth factors. And the scaffold material is a hot spot in
the research of tissue engineering in recent years. Electrospinning can produce polymer fibers with diameters down to
nanoscale dimensions and form high porosity non-woven mat. This paper introduces the application of electrospinning
technology in the cartilage tissue engineering.

      【Key words】 Tissue engineering; Scaffolds; Electrospinning; Cartilage
·综 述·
doi:10.3969/j.issn.1003-6350.2016.19.034