标题：参苓白术散加减辅助治疗2型糖尿病伴肥胖症80例临床观察

      作者：徐小娟，刘 丹，王 静
    (深圳市福田区中医院内一科，广东 深圳 518034)

      卷次： 2015年26卷24期

      【摘要】 目的 观察参苓白术散加减辅助治疗2型糖尿病伴肥胖症的临床疗效。方法 选取符合纳入标准
的 2型糖尿病伴肥胖症患者 80例，随机分为观察组和对照组各 40例，两组均给予胰岛素治疗(三短一长)，观
察组在胰岛素治疗基础上加服参苓白术散加减方，疗程 12周，观察两组治疗前后空腹血糖(FPG)、餐后 2 h血
糖(2 hPG)、糖化血红蛋白(HbA1c)、体重指数(BMI)、腰臀比(WHR)，评判疗效。结果 观察组患者治疗后的FPG、
2 hPG、HbA1c、BMI、WHR明显好于对照组，差异均有统计学意义（P<0.05），且服药期间无明显不良反应，依从性
好。结论 参苓白术散加减方可有助降低血糖、减轻体重，对于2型糖尿病伴肥胖症患者，具有较好疗效。

      【关键词】 2型糖尿病；肥胖症；参苓白术散；中医药疗法

      【中图分类号】 R587.1 【文献标识码】 A 【文章编号】 1003—6350（2015）24—3612—03


Clinical effect of additive Shenlingbaizhusan decoction in the treatment of 80 patients with type 2 diabetes
mellitus complicated with obesity.
XU Xiao-juan, LIU Dan, WANG Jing. The First Department of Internal Medicine,
Shenzhen Futian District TCM Hospital, Shenzhen 518034, Guangdong, CHINA

【Abstract】 Objective To observe the effect of additive shenlingbaizhusan decoction in the treatment of type
2 diabetes mellitus (T2DM) complicated with obesity. Methods Eighty patients of T2DM complicated with obesity
were selected and randomly divided into two groups: the treatment group (n=40) and the control group (n=40). The
two groups were both treated with insulin therapy, and the treatment group was treated additionally with shenlingbai-
zhusan therapy. The course of treatment was 12 weeks. The level of fasting plasma glucose (FPG), 2-hour plasma glu-
cose (2 hPG), glycosylated hemoglobin A1c (HbA1c), body mass index (BMI) and waist-hip ratio (WHR) of the two
groups were observed, and the clinical efficacy was evaluated. Results In the treatment group, the FPG, 2 hPG,
HbA1c, BMI and WHR were significantly better than those in the control group, with no obvious adverse reaction and
good comp1iance. Conclusion Shenlingbaizhusan can down-regulate the level of blood glucose and contribute to
weight loss, which has great clinical effect for patients of T2DM complicated with obesity.

      【Key words】 Type 2 diabetes mellitus; Obesity; Shenlingbaizhusan; Traditional Chinese medical therapy