标题：腹膜透析相关性腹膜炎的致病原因及影响因素分析

      作者：万 力，何川鄂，杨 林，夏 雪
    (三峡大学第一临床医学院宜昌市中心人民医院肾病科，湖北 宜昌 443003)

      卷次： 2015年26卷21期

      【摘要】 目的 探讨腹膜透析相关性腹膜炎的致病原因及影响因素。方法 回顾性分析 2012年 4月至
2014年11月我院肾病科收治的40例腹膜透析相关性腹膜炎患者的临床资料，从患者的性别、年龄、发病季节、透
析龄、发病原因及医疗保险类型、预后等方面进行分析，并总结致病菌种类。结果 40例患者共发生51例次腹膜
炎，治愈31例(77.50%)，腹膜透析退出率为22.50%；女性明显多于男性；透析龄1年以上的患者占多数(84.31%)；城区
医疗保险的患者(77.50%)多于农村合作医疗的患者(22.50%)；腹膜炎的发生受季节影响不大；发病原因主要为操作
不规范(41.18%)；致病菌以表皮葡萄球菌(63.64%)多见；真菌性腹膜炎患者的腹膜透析退出率为100%。结论 腹膜
透析相关性腹膜炎的发病与性别、透析龄等因素相关，多因操作不当所致，在患者的随访过程中，应加强对患者
操作技术以及腹膜炎防治相关知识的再培训。

      【关键词】 腹膜透析；腹膜炎；透析龄

      【中图分类号】 R656.4+1 【文献标识码】 A 【文章编号】 1003—6350（2015）21—3195—03


Clinical study on causes and influencing factors of peritoneal dialysis-related peritonitis.
WAN Li, HE Chuan-e,
YANG Lin, XIA Xue. Department of Nephropathy, the First Clinic College of China Three Gorges University, Central
People's Hospital of Yichang, Yichang 443003, Hubei, CHINA

【Abstract】 Objective To investigate the etiological and risk factors of peritoneal dialysis-related peritoni-
tis, as well as the influencing factors. Methods Forty patients of peritoneal dialysis-related peritonitis in our hospi-
tal from April 2012 to November 2014 were retrospectively analyzed from gender, age, disease-onset seasons, dialy-
sis age, etiological factors, types of medical insurance and prognosis. The types of pathogenic bacteria were summa-
rized. Results During the study period, 51 episodes of peritonitis were recorded for the 40 patients, of which 31
(77.50%, 31/40) were cured, and 22.50% dropped out peritoneal dialysis. Among the 40 patients, female patients were
significantly more than male ones. Patients of dialysis age for over 1 year were in the majority, accounting for 84.31%.
Patients of urban medical insurance (77.50%) were significantly more than those of rural cooperative medical service
(22.50%). Disease-onset seasons had little effect on peritoneal dialysis-related peritonitis. Etiological factors were main-
ly unstandardized operation (41.18% ). The most common pathogenic bacteria were Staphylococcus epidermidis
(63.64%). All the patents of fungal peritonitis dropped out peritoneal dialysis, with the rate of 100%. Conclusion Peri-
toneal dialysis-related peritonitis is closely related with the patients' gender, dialysis age, which were mainly caused by
unstandardized operation. Operating technique and prevention knowledge to peritoneal dialysis-related peritonitis
should be strengthened and retrained during follow-up.