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      标题:脂筏结构在细胞内蛋白质运输中的作用
      作者:刘卫霞 1,祝 贺 2,邢艳霞 2
    (1.山东中医药大学附属医院核医学科,山东 济南 250011;
2.山东农业工程学院,山东 济南 250100)
      卷次: 2015年26卷21期
      【摘要】 在细胞膜中存在由胆固醇、鞘糖脂以及蛋白质等成分组成的液态有序的结构,叫做脂筏。从内质
网到高尔基体再到细胞质膜,脂筏结构在细胞膜中所占的比例越来越高。脂筏在高尔基体到细胞质膜的物质转
运以及细胞内吞、再循环过程中发挥着重要的作用。本文将就脂筏结构在物质从高尔基体到质膜的转运和细胞
内吞过程中的作用及其分子机制做一综述。

      【关键词】 脂筏;蛋白质运输;内质网;高尔基体;内吞

      【中图分类号】 R329.2+7 【文献标识码】 A 【文章编号】 1003—6350(2015)21—3179—04


Function of lipid raft in protein transport.

LIU Wei-xia 1, ZHU He 2, XING Yan-xia 2. 1. Department of Nuclear
Medicne, Affiliated Hospital of Shandong University of Tranditional Chinese Medicine, Jinan 250011, Shandong, CHINA;
2. Shandong Agriculture and Engineering University, Jinan 250100, Shandong, CHINA
【Abstract】 The ordered liquid structure composed of cholesterol, glycosphingolipid and protein in cell mem-
brane is called lipid raft. The proportion of lipid raft in cell membrane becomes higher from endoplasmic reticulum to
Golgi apparatus and then to plasma membrane. Lipid raft plays an important role in the protein transport from Golgi
apparatus to plasma membrane, in endocytosis and recycling. This review will focus on the function and molecular
mechanism of lipid raft in the protein transport from Golgi apparatus to plasma membrane and endocytosis.

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