标题：海南地区消化疾病谱初步调查研究

      作者：罗开发 1，李 闻 2，王永华 2，王巍峰 2，李 贞 2，孟 科 3，赵 丽 3，王婷婷 3
    （1.中国人民解放军281医院呼吸消化科，河北 秦皇岛 066100；
2.中国人民解放军总医院消化内科，北京 100853；
3.中国人民解放军总医院海南分院消化内科，海南 三亚 572013）

      卷次： 2015年26卷18期

      【摘要】 目的 初步探讨海南消化门诊患者的疾病谱特点，为进一步开展全国多中心研究热带气候对消化
疾病的影响做准备。方法 通过问卷的形式，调查解放军总医院海南分院消化科 2012年 12月，2013年 3月、6
月、9月门诊患者消化系疾病谱的分布情况。结果 发放问卷 778份，合格问卷 743份，合格率为 95.5%。入选
743例中男性408例，女性335例，平均年龄(43.6±15.4)岁；本地人群480例，“候鸟人群”159例，游客人群104例。
三组人群的传染病患病率比较差异有统计学意义(P=0.022)，其中以乙肝最为显著，本地人群、候鸟人群患病比例
高于游客人群(P<0.05)；三组人群中急性胃肠炎和胃食管反流病患病率比较差异有统计学意义，研究显示游客人
群急性胃肠炎和胃食管反流病患病比例高于本地人群、候鸟人群(P<0.05)；三组间的幽门螺杆菌(HP)感染率比较
差异有统计学意义，且本地人群、候鸟人群均高于游客人群(P<0.05)。消化系肿瘤、肝胆胰系疾病三组间比较差
异无统计学意义(P>0.05)。结论 热带气候对消化系疾病谱有作用，进一步开展全国多中心研究热带气候对消
化疾病的干预很有必要。

      【关键词】 消化系疾病；气候；海南

      【中图分类号】 R57 【文献标识码】 D 【文章编号】 1003—6350（2015）18—2785—04


Preliminary investigation on the digestive disease spectrum in Hainan province.
LUO Kai-fa 1, LI Wen 2, WANG
Yong-hua 2, WANG Wei-feng 2, LI Zhen 2, MENG Ke 3, ZHAO Li 3, WANG Ting-ting 3. 1. Department of Respiratory
and Digestive Diseases, the 281 Hospital of Chinese People's Liberation Army, Qinhuangdao 066100, Hebei, CHINA;
2. Department of Gastroenterology, the General Hospital of Chinese People's Liberation Army, Beijing 100853, CHINA;
3. Department of Gastroenterology, Hainan Branch, the General Hospital of Chinese People's Liberation Army, Sanya
572013, Hainan, CHINA

【Abstract】 Objective To explore the disease spectrum characteristics of Department of Gastroenterology in
Hainan, to lay basis for the further development of a national multicenter study of tropical climate effects on digestive
diseases. Methods By questionnaires, the changes and distribution of outpatients with digestive disease spectrum was
investigated in Dec. 2012, Mar., Jun., Sep. 2013 in Department of Gastroenterology, Hainan Branch, the General Hospi-
tal of Chinese People's Liberation Army. Results Of the 778 questionnaires issued, 743 questionnaires were qualified
(with the qualification rate of 95.5%), involving 408 males and 335 females, with the mean age of (43.6±15.4) years.
Among the 743 patients, there were 480 cases of local population, 159 cases of migratory population, 104 cases of tourists.
The prevalence of infectious diseases in the three groups of population showed statistically significant difference (P=
0.022). The most significant disease was hepatitis B, the prevalence of which was significantly higher in local population,