标题：儿童行全身麻醉手术对其智力和感觉统合能力的影响

      作者：朱 明，王 璐
    (上海市儿童医学中心麻醉科，上海 200127)

      卷次： 2015年26卷18期

      【摘要】 目的 研究儿童接受全身麻醉手术后对智力和感觉统合能力的影响。方法 选取1~3岁期间进行
过全身麻醉非心脏外科、神经外科手术的7~9岁儿童为实验组(n=72)；根据每例实验组儿童的性别、年龄、父母教
育背景、文化程度、职业等按照 1：1匹配原则选取 1~3岁期间未进行全麻手术的 7~9岁儿童作为对照组(n=72)。
分别利用韦氏儿童智力量表、儿童感觉统合能力发展评定表评定入选儿童的智力和感觉统合能力。结果 两组
儿童的总智商和认知能力指数比较差异均无统计学意义(P>0.05)。在智力内部结构方面，实验组儿童的言语理
解-加工速度指数存在差异者为16.7%(12/72)，而对照组为1.4%(1/72)，实验组的知觉推理-加工速度指数差异者
为 20.8%，(15/72)，对照组为 2.8%(2/72)，两组指数比较差异均具有统计学意义(P<0.05)；实验组儿童前庭功能失
衡发生率为25.0%(18/72)，明显高于对照组儿童的1.4%(1/72)，差异具有统计学意义(P<0.05)。结论 总体来看，
儿童在1~3岁期间进行全麻手术后对其后期的智力、感觉统合能力无显著影响，但实验组儿童在知觉推理-加工
速度指数和工作记忆-言语理解指数差异明显；儿童接受全麻手术后对其前庭功能有一定影响。

      【关键词】 全身麻醉；儿童；智力；感觉统合能力

      【中图分类号】 R726 【文献标识码】 A 【文章编号】 1003—6350（2015）18—2701—03


Effect of general anesthesia for children on their intelligence and sensory integration capability.
ZHU Ming,
WANG Lu. Department of Anesthesiology, Shanghai Children's Medical Center, Shanghai 200127, CHINA

【Abstract】 Objective To study the effect of general anesthesia on children's intelligence and sensory integra-
tion capability. Methods Children aged 7~9 who had gone through general anesthesia during the age from 1 to 3 but
not for cardiac surgery or neurosurgery were selected as the experimental group (n=72). Children aged 7~9 who re-
ceived no general anesthesia during the age from 1 to 3 were selected as the control group (n=72) based on the 1:1
principle correspondent with sex, age, and education, education levels, occupation of their parents of the experimental
group. The Wechsler Intelligence Scale and Children Sensory Integration Capability Development Rating were used to
assess the children's intelligence and capability of sensory integration. Results The two groups of children showed
no statistically significant difference in the total index of intelligence and cognitive ability (P>0.05). In terms of the in-
ternal structure of intelligence, the proportion of patients in the experimental group who were with difference between
perceptual reasoning index and processing speed index was 16.7% (12/72), and that in the control group was 1.4%
(1/72). Proportion of patients in the experimental group who were with difference between working memory and the
verbal comprehension index was 20.8% (15/72), and that of the control group was 2.8% (2/72). Both the above com-
parisons showed statistically significant differences (P<0.05). The incidence rate of vestibular imbalance in the ex-
perimental group was 25% (18/72), significantly higher than that in the control group [14% (1/72)], with significant
difference (P<0.05). Conclusion Generally, children who received general anesthesia operation during 1 to 3
years old show no significantly difference in the intellectual, sensory integration ability, but the children of experi-
mental group show significant difference in the perceptual reasoning index and processing speed as well as working
memory and the verbal comprehension index. Besides, general anesthesia produces some effect on children's vestib-
ular function.

      【Key words】 General anesthesia; Children; Intelligence; Sensory integrative capability