标题：小儿EB病毒感染性咽炎与肠系膜淋巴结炎的相关性研究

      作者：邓爱芬 1，肖满田 2，叶秩坤 1，张庭艳 2
    (1.广州医学院荔湾医院儿科，广东 广州 510170；
2.广州市妇女儿童医疗中心儿科，广东 广州 510623)

      卷次： 2015年26卷13期

      【摘要】 目的 探讨小儿EB病毒感染性咽炎与肠系膜淋巴结炎的关系。方法 选择160例同时存在咽炎
及消化道症状的患儿为研究对象，检测其EB病毒特异性抗体（EBV-VCA-IgM）情况，并行腹部超声检查。比较
EBV-VCA-IgM阳性者和阴性者患儿患肠系膜淋巴结炎情况及其淋巴结长径、同切面淋巴结数量及淋巴结内血
流情况。结果 160例患儿中，EBV-VCA-IgM阳性者 62例，阴性者 98例。阳性者患肠系膜淋巴结炎 16例，占
25.8%，阴性者7例，占7.1%，阳性者高于阴性者，差异具有统计学意义(P<0.05)；EBV-VCA-IgM阳性者患儿肠系
膜淋巴结长径大于阴性者，同切面淋巴结数量多于阴性组，差异均具有统计学意义(P<0.05)；两组患儿的淋巴结
血流比较差异也有统计学意义(P<0.05)。结论 EB病毒感染性咽炎患儿发生肠系膜淋巴结炎的比例高，超声学
表现具有明显改变。

      【关键词】 EB病毒；咽炎；肠系膜淋巴结炎；小儿

      【中图分类号】 R729 【文献标识码】 A 【文章编号】 1003—6350（2015）13—1918—03


Correlation between pharyngitis with Epstein-Barr virus infection and mesenteric lymphadenitis in children.
DENG Ai-fen 1, XIAO Man-tian 2, YE Zhi-kun 1, ZHANG Ting-yan 2.
1. Department of Pediatrics, Liwan Hospital,
Guangzhou Medical College, Guangzhou 510170, Guangdong, CHINA; 2. Department of Pediatrics, Guangzhou Women
and Children's Medical Center, Guangzhou 510623, Guangdong, CHINA

【Abstract】 Objective To explore the relationship between pharyngitis with Epstein-Barr virus (EBV) in-
fection and mesenteric lymphadenitis in children. Methods One hundred and sixty children with simultaneous pres-
ence of pharyngitis and gastrointestinal symptoms were chosen as the research subjects. EB virus specific antibody
(EBV-VCA-IgM) was detected, and parallel abdominal ultrasonography were performed. Mesenteric lymphadenitis,
the long diameter of lymph node, the number of lymph node in the same section, and blood flow of lymph node were
compared between EBV-VCA-IgM positive and negative patients. Results In the 160 cases, there were 62 cases
of EBV-VCA-IgM positive and 98 cases of EBV-VCA-IgM negative. Sixteen of the EBV-VCA-IgM positive cases
were found with mesenteric lymphadenitis, accounting for 25.8% (16/62), and 7 of the EBV-VCA-IgM negative cas-
es were with mesenteric lymphadenitis (7.1%,7/98), with statistically significant difference (P<0.05). The long diam-
eter of lymph node in EBV-VCA-IgM positive children was greater than that in the negative ones, and the number of
lymph node in the same section of EBV-VCA-IgM positive children was more, with statistically significant differ-
ence (P<0.05). There were also significant differences in blood flow of lymph node between the two groups (P<
0.05). Conclusion Children of pharyngitis with EB virus infection have a high proportion of mesenteric lymphadeni-
tis, with significantly changed ultrasonic features.

      【Key words】 EB virus; Pharyngitis; Mesenteric lymphadenitis; Children