标题：Non-HDL-C和AI对冠心病患者病情的评估价值

      作者：王秋颖 1，向良浩 1，张伟民 1，吴 兴 1，王鲁英 2
    (中国人民解放军第九二医院心血管内分泌科 1、胸心普外科 2，福建 南平 353000)

      卷次： 2015年26卷13期

      【摘要】 目的 探讨非高密度脂蛋白(Non-HDL-C)和粥样动脉硬化指数(AI)评估冠心病病情的临床价值。
方法 以冠心病患者为病例组(398例)，以健康者为对照组(150例)，全自动生化分析仪检测并比较不同组别受试
者的一般临床资料、血脂、血糖、Non-HDL-C、AI等指标。结果 冠心病组年龄、BMI、血压、甘油三酯、
Non-HDL-C、AI等均高于对照组(P<0.05)；慢性冠心病组年龄、BMI、收缩压、甘油三酯、TC、LDL-C、HDL-C、空腹
血糖、Non-HDL-C、AI等高于不稳定型心绞痛组、急性心肌梗死组(P<0.05)；Non-HDL-C与AI具有正相关关系
(r2=0.161 1，P<0.05)；Non-HDL-C、AI均与年龄、HDL-C呈负相关，与 LDL-C、TC、甘油三酯呈正相关(P<0.05)；
Non-HDL-C、AI与冠状动脉病变总分呈正相关(P<0.05)。结论 冠心病患者的Non-DHL-C和AI水平明显高于
对照组，且Non-DHL-C和AI水平越高，冠心病病变越严重。二者可用于评价冠心病病情严重程度。

      【关键词】 非高密度脂蛋白(Non-HDL-C)；粥样动脉硬化指数(AI)；冠心病；价值

      【中图分类号】 R541.4 【文献标识码】 A 【文章编号】 1003—6350（2015）13—1909—04


Value of non-high-density lipoprotein cholesterol and atherosclerosis index for assessing the illness of patients
with coronary heart disease.
WANG Qiu-ying 1, XIANG Liang-hao 1, ZHANG Wei-min 1, WU Xing 1, WANG Lu-ying 2.
Department of Cardiovascular Endocrinology 1, Department of Cardiothoracic General Surgery 2, the 92nd Hospital of
Chinese People's Liberation Army, Nanping 353000, Fujian, CHINA

【Abstract】 Objective To investigate the value of non-high-density lipoprotein cholesterol (non-HDL-C) and
atherosclerosis index (AI) for determining the illness of the patients with coronary heart disease. Methods Patients
with coronary artery disease (CHD group, n=398) and normal healthy people (control group, n=150) were selected and
tested by automatic biochemical analyzer. The clinical data were compared and between the two groups, including blood
lipid, blood sugar, non-HDL-C and AI. Results The age, body mass index (BMI), blood pressure, triglycerides,
non-HDL-C, AI of CHD group were higher than those of the control group (P<0.05). The age, BMI, systolic blood pres-
sure, triglycerides, total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol
(HDL-C), fasting glucose, non-HDL-C, AI of chronic CHD group were higher than those of unstable angina group and
acute myocardial infarction group (P<0.05). Non-HDL-C and AI had positive correlation (r2=0.161 1, P<0.05), and
non-HDL-C, AI were negatively associated with age, HDL-C and positively correlated with LDL-C, TC, TG (P<0.05).
Non-HDL-C, AI and coronary lesion scores were positively correlated (P<0.05). Conclusion Non-DHL-C and AI levels
are significantly higher in patients with coronary heart disease than healthy people. The higher the non-DHL-C and AI lev-
els are, the more severe the disease is. The two indexes can be used for evaluating the severity of coronary artery disease.

      【Key words】 Non-high-density lipoprotein cholesterol (non-HDL-C); Atherosclerosis index (AI); Coronary ar-
tery disease; Value