标题：卵巢外腹膜浆液性乳头状癌24例临床病理研究

      作者：刘清华，谢寿城
    (梅州市人民医院病理科，广东 梅州 514031)

      卷次： 2015年26卷12期

      【摘要】 目的 探讨卵巢外腹膜浆液性乳头状癌(EPSPC)的临床和病理特点。方法 回顾性分析2000-2012
年我院收治的24例EPSPC患者及90例卵巢浆液性乳头状癌(OPSC)患者的临床和病理资料。结果 EPSPC患者的
临床特征与OPSC相似。免疫组化结果显示，EPSPC患者的雌激素受体(ER)、孕激素受体(PR)及P53表达阳性率分
别为 25%、37.5%和 33.3%，明显低于 OPSC患者的 66.7%、80%和 65.6%，差异均有统计学意义 (P<0.05)。
结论 EPSPC患者的临床特点及组织学特征与 OPSC相似，ER、PR、P53检测可为两者的鉴别诊断提供
一定的依据，而卵巢无或仅微小浸润仍是目前区分两者的主要标准。

      【关键词】 卵巢外腹膜浆液性乳头状癌；卵巢浆液性乳头状癌；免疫组化；临床病理特点

      【中图分类号】 R737.31 【文献标识码】 A 【文章编号】 1003—6350（2015）12—1848—02


A clinicopathological study on 24 cases of extraovarian peritoneal serous papillary carcinoma.
LIU Qing-hua,
XIE Shou-cheng. Department of Pathology, Meizhou People's Hospital, Meizhou 514031, Guangdong, CHINA

【Abstract】 Objective To study the clinicopathological features of extraovarian peritoneal serous papillary
carcinoma (EPSPC). Methods The clinicopathological data of 24 patients of EPSPC and 90 patients of ovarian papil-
lary serous carcinoma (OPSC) treated in our hospital from January 2007 to December 2012 were retrospectively ana-
lyzed. Results The clinical features of EPSPC were similar to those of OPSC. The expressions of estrogen receptor
(ER), progesterone receptor (PR) and P53 in EPSPC (25%, 37.5% and 33.3%, respectively) were significantly lower
than those in OPSC (66.7%, 80% and 65.6%, respectively) (P<0.05). Conclusion The clinical and histological char-
acteristics of EPSPC are similar to those of OPSC. ER, PR and P53 may be useful markers for distinguishing EPSPC
from OPSC, but the ovarian without infiltration or with slight infiltration only is still the main criterion.

      【Key words】 Extraovarian peritoneal serous papillary carcinoma (EPSPC); Ovarian papillary serous carcino-
ma (OPSC); Immunohistochemistry; Clinicopathological features