标题：牛奶蛋白过敏患儿的营养干预研究

      作者：邓爱芬 1，肖满田 1，叶秩坤 1，张庭艳 2
    (1.广州医学院荔湾医院儿科，广东 广州 510170；
2.广州市妇女儿童医疗中心儿科，广东 广州 510623)

      卷次： 2015年26卷12期

      【摘要】 目的 探讨牛奶蛋白过敏(CMPA)患儿的营养干预方法及效果。方法 采用自身对照研究方法，
回顾性分析79例CMPA患儿的临床资料，均予以牛奶回避及氨基酸配方粉等营养干预治疗，观察并比较患者干
预前及干预后 3个月的消化道症状、实验室指标及临床疗效。结果 患者干预 3个月后消化道症状、血红蛋白
(Hb)及血嗜酸性细胞等均有明显改善，与干预前比较差异均有统计学意义(P<0.05)；干预3个月后患儿的总有效
率为93.7%，与干预1个月后的78.5%比较，差异有统计学意义(P<0.05)。结论 使用氨基酸配方粉等营养干预的
方法治疗CMPA患儿的效果显著，值得临床推广。

      【关键词】 牛奶蛋白过敏；牛奶回避；营养干预；氨基酸；效果

      【中图分类号】 R153.2 【文献标识码】 A 【文章编号】 1003—6350（2015）12—1753—03


Study on nutritional intervention in children with milk protein allergy.
DENG Ai-fen 1, XIAO Man-tian 1, YE
Zhi-kun 1, ZHANG Ting-yan 2. 1. Department of Pediatrics, Liwan Hospital, Guangzhou Medical College, Guangzhou
510170, Guangdong, CHINA; 2. Department of Pediatrics, Guangzhou Women and Children's Medical Center, Guangzhou
510623, Guangdong, CHINA

【Abstract】 Objective To investigate the nutrition intervention method and its effect in the treatment of chil-
dren with milk protein allergy (CMPA). Methods Based on self-controlled study, the clinical data of 79 children
with CMPA were retrospective analyzed, which were all treated with milk avoidance and amino acid formula powder
for nutrition intervention. Changes of gastrointestinal symptoms, laboratory indexes and clinical therapeutic effect
were observed before and 3 months after treatment. Results Three months after intervention, the gastrointestinal
symptoms, hemoglobin (Hb) and blood eosinophilia acidic cells were significantly improved, and there were signifi-
cantly differences compared with before treatment (P<0.05). The total effective rate after 3 months was 93.7%, signifi-
cantly higher than 78.5% one month after treatment (P<0.05). Conclusion Nutrition intervention has remarkable ef-
fect in the treatment of CMPA and is worthy of clinical promotion.