标题：管状胃对食管癌术后胃食管返流的影响

      作者：殷汉华，李瑞华，肖敬东
    (河源市中医院消化内科，广东 河源 517000)

      卷次： 2015年26卷10期

      【摘要】 目的 探讨管状胃对食管癌术后患者胃食管返流的影响。方法 86例食管癌患者随机分为观察
组和对照组各43例，均接受食管癌手术治疗。观察组给予管状胃代食管吻合术，对照组给予全胃代食管吻合术，
比较两组患者术后的胃食管返流情况。结果 观察组患者24 h酸返流次数、≥5 min酸返流次数均少于对照组，
差异均有显著统计学意义(P<0.01)；最长酸返流时间、pH＜4总时间均短于对照组，差异均有显著统计学意义(P<
0.01)；观察组患者术后1个月、3个月时的RDQ评分均低于对照组，且胃食管返流发生率也低于对照组，差异均有
显著统计学意义(P<0.01)。结论 管状胃用于食管癌患者术中食管重建能够有效减轻患者术后的胃食管返流程
度，降低胃食管返流发生率，对于患者术后生活质量的提高具有重要临床意义。

      【关键词】 管状胃；食管癌；胃食管返流

      【中图分类号】 R735.1 【文献标识码】 A 【文章编号】 1003—6350（2015）10—1434—03


Influence of tube gastroesophagostomy on gastroesophageal reflux after radical resection of esophageal
carcinoma.
YIN Han-hua, LI Rui-hua, XIAO Jing-dong. Department of Gastroenterology, Heyuan Hospital of
Traditional Chinese Medicine, Heyuan 517000, Guangdong, CHINA

【Abstract】 Objective To discuss the clinical influence of tube gastroesophagostomy on gastroesophageal re-
flux in patients with esophageal carcinoma. Methods Eighty-six patients with esophageal carcinoma were divided in-
to the observation group (n=43) and the control group (n=43), which all received radical resection. After operation, the
observation group was given tube gastroesophagostomy, while the control group was given whole gastroesopha-
gostomy. Then the gastroesophageal reflux status was compared between the two groups. Results Episodes of
gastric acid reflux in 24 h, Episodes of gastric acid reflux more than 5 min were less in the observation group than
the control group, and the difference was statistically significant (P<0.01). The longest acid reflux time, total time
of pH<4 were shorter in the observation group than the control group, and the difference was statistically signifi-
cant (P<0.01). RDQ scores 1, 3 months after operation were significantly lower in the observation group than the
control group (P<0.01), and the gastroesophageal reflux rate was also significantly lower in the observation group
(P<0.01). Conclusion Tube gastroesophagostomy can effectively reduce postoperative gastroesophageal reflux de-
gree, reduce gastroesophageal reflux rate in patients with esophageal cancer. It has important clinical significance to
improve the quality of life in postoperative patients.

      【Key words】 Tube gastroesophagostomy; Esophageal Cancer; Gastroesophageal reflux
·论 著·doi:10.3969/j.issn.1003-6350.2015.10.0512