标题：靶向超声微泡在卵巢癌治疗中的研究进展

      作者：苏子涵，赵 云
    （三峡大学医学院，湖北 宜昌 443000）

      卷次： 2015年26卷9期

      【摘要】 近年来，随着对超声生物效应的深入研究，各种兼具诊断治疗双重作用的超声探头及靶向微泡造
影剂的研制逐渐成为热点。靶向超声微泡作为一种新的基因或药物有效运载工具，通过携带基因或药物对肿瘤
组织靶向释放，介导肿瘤细胞坏死、凋亡以及肿瘤微血管的栓塞和阻断，从而达到靶向治疗的目的。目前，超声
微泡介导靶向治疗卵巢癌也展现出了良好的前景，本文就其研究进展进行简要综述。

      【关键词】 超声微泡；靶向治疗；卵巢癌

      【中图分类号】 R737.31 【文献标识码】 A 【文章编号】 1003—6350（2015）09—1331—04


Reaserch progress of targeted ultrasonic microbubble in the treatment of ovarian cancer.
SU Zi-han, ZHAO
Yun. Department of Ultrasonography, the Second Clinical Medical College of China Three Gorges University, Yichang
443000, Hubei, CHINA
【Abstract】 In recent years, with the in-depth study of ultrasonic biological effects, development of ultrasonic
probe and targeted microbubble contrast agent has gradually become a hot spot. Targeted ultrasound microbubble, as a
kind of new gene or effective carrier of drug, achieved its purpose of targeted therapy by carrying genes or drugs
for tumor targeting release, and mediating tumor cell necrosis and apoptosis and tumor microvascular thrombosis
and blocking. At present, ultrasound microbubble targeting therapy for ovarian cancer has showed good prospects.
Therefore, the research progress of ultrasound microbubble targeting therapy for ovarian cancer was reviewed in
this article.