标题：北细辛原粉及其不同提取物抗炎作用初探

      作者：魏新智，王清华，付勇强，王 珲，王 英，尤春来，孙科峰
    (辽宁中医药大学附属医院中医药实验中心，辽宁 沈阳 110032)

      卷次： 2015年26卷9期

      【摘要】 目的 初步探讨北细辛原粉及其不同提取物的抗急性炎症作用。方法 采用巴豆油引起的小鼠
耳肿胀法和角叉菜胶引起的大鼠足爪肿胀法，观察北细辛原粉及其不同提取物的抗急性炎症作用。结果 北细
辛原粉低、中、高剂量组及北细辛挥发油低、中、高剂量组均有抑制小鼠耳肿胀作用；挥发油高剂量组还具有抑制
及大鼠足趾肿的作用。结论 北细辛原粉及北细辛挥发油有抗急性炎症作用。

      【关键词】 北细辛；急性炎症；小鼠；大鼠

      【中图分类号】 R-332 【文献标识码】 A 【文章编号】 1003—6350（2015）09—1253—03


Anti-inflammatory roles of Asarum original powder and different extracts in experimental research.
WEI
Xin-zhi, WANG Qing-hua, FU Yong-qiang, WANG Hui, WANG Ying, YOU Chun-lai, SUN Ke-feng. Experiment Center
of Traditional Chinese Medicine, the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang
110032, Liaoning, CHINA

【Abstract】 Objective To explore the roles of Asarum original powder and different extracts against acute
inflammation. Methods The anti-inflammatory roles of of Asarum original powder and extracts were observed by
investigating their effect against croton oil-induced mouse ear swelling and carrageenan-induced rat paw swelling.
Results The Asarum original powder of low, medium and high dose and volatile oils of low, medium and high dose
all can inhibit mouse ear swelling. Volatile oil of high dose can also inhibit rats paw swelling. Conclusion The Asa-
rum original powder and volatile oil have anti-inflammatory effect.