标题：视黄醇结合蛋白和前白蛋白评价早产儿营养状况的价值

      作者：谢金水，徐燕珊，黄妙霞
    (东莞市第三人民医院儿科，广东 东莞 523320)

      卷次： 2015年26卷8期

      【摘要】 目的 探讨视黄醇结合蛋白和前白蛋白评价早产儿营养状况的价值。方法 选取在我院分娩的
早产儿98例为观察组，同时选取同期在我院分娩的足月儿98例为对照组，并根据观察组新生儿胎龄的不同将胎
龄<34周的53例新生儿分为A组，胎龄≥34周的45例新生儿分为B组。所有新生儿均检测血清白蛋白、前白蛋
白和视黄醇结合蛋白的水平，对比观察组和对照组，A组和B组新生儿的血清白蛋白、前白蛋白和视黄醇结合蛋
白的水平。结果 观察组的血清白蛋白水平为(30.13±3.84) g/L，前白蛋白水平为(23.91±3.93) mg/L，视黄醇结合
蛋白水平为(122.83±24.47) mg/L，均显著低于对照组的相应指标，差异均有统计学意义(P<0.05)；A组的血清白蛋
白水平为(29.06±5.28) g/L，前白蛋白水平为(19.89±5.91) mg/L，视黄醇结合蛋白水平为(110.08±21.14) mg/L，均显
著低于B组的相应指标，差异均有统计学意义(P<0.05)。结论 视黄醇结合蛋白、前白蛋白的检测可更为准确、
敏感地反映早产儿的营养状况，为临床营养支持治疗方案的制定提供依据。

      【关键词】 视黄醇结合蛋白；前白蛋白；早产儿；营养状况

      【中图分类号】 R722 【文献标识码】 A 【文章编号】 1003—6350（2015）08—1165—03


Value of retinol binding protein and prealbumin in the evaluation of preterm infant nutrition.
XIE Jin-shui, XU
Yan-shan, HUANG Miao-xia. Department of Paediatrics, the Third People's Hospital of Dongguan City, Dongguan
523320, Guangdong, CHINA

【Abstract】 Objective To investigate the value of retinol binding protein and prealbumin in the evaluation of
preterm infant nutrition. Methods Ninety-eight premature infants were selected in our hospital as the observation
group, and at the same time, 98 full-term infants were selected in our hospital as the control group. According to gesta-
tional age difference, the 98 premature infants were divided into group A (53 neonates with gestational age <34 weeks)
and group B (45 neonates with gestational age ≥34 weeks). The level of prealbumin and retinol binding protein, se-
rum albumin of all newborns were detected and compared. Results The level of serum albumin, prealbumin, retinol
binding protein in the observation group was (30.13±3.84) g/L, (23.91±3.93) mg/L, (122.83±24.47) mg/L, respective-
ly, which were all significantly lower than the corresponding index in the control group (P<0.05). The level of the
three proteins in group A was (29.06±5.28) g/L, (19.89±5.91) mg/L, (110.08±21.14) mg/L, respectively, significantly
lower than the corresponding index of group B (P<0.05). Conclusion The detection of prealbumin and retinol bind-
ing protein can more accurately, sensitively reflect the nutritional status in premature infants, which can provide basis
for clinical nutrition support therapy.