标题：胃癌术后功能性胃排空障碍相关危险因素分析

      作者：魏红霞 1，卢红元 2
    (1.商洛市商州区人民医院消化内科，陕西 商洛 726000；
2.陕西省康复医院，陕西 西安 710065)

      卷次： 2015年26卷7期

      【摘要】 目的 分析胃癌术后功能性胃排空障碍(FDGE)的危险因素。方法 选择2011年4月至2014年4
月在我院接受胃癌根治术治疗的患者153例作为研究对象，根据是否发生FDGE分为FDGE组45例，无FDGE组
108例。先对胃癌术后发生FDGE进行单因素分析，并进一步根据Logistic回归法分析胃癌术后发生FDGE的危
险因素。结果 FDGE组在术后血糖>8 mmol/L、围术期的白蛋白水平≤30 g/L、手术前有胃潴留、吻合方式为
BillrothⅡ式、未保留迷走神经干及有焦虑情绪等方面的比例均显著高于无FDGE组，差异均有统计学意义(P<
0.05)。根据Logistic回归分析后发现，术后血糖＞8 mmol/L、围术期的白蛋白水平≤30 g/L、手术前有胃潴留、吻
合方式为BillrothⅡ式、未保留迷走神经干以及有焦虑情绪等均为胃癌术后发生FDGE的危险因素。结论 影响
胃癌术后FDGE的危险因素较多，临床上应予以重视。

      【关键词】 胃癌；功能性胃排空障碍；危险因素；分析

      【中图分类号】 R735.2 【文献标识码】 A 【文章编号】 1003—6350（2015）07—0974—03


Risk factors analysis of functional delayed gastric emptying after gastric cancer radical operation.
WEI
Hong-xia 1, LU Hong-yuan 2. 1. Department of Gastroenterology, Shangzhou District People's Hospital of Shangluo,
Shangluo 726000, Shaanxi, CHINA; 2. Rehabilitation Hospital of Shaanxi Province, Xi’an 710065, Shaanxi, CHINA

【Abstract】 Objective To study the risk factors analysis of functional delayed gastric emptying (FDGE) after
gastric cancer radical operation. Methods A total of 153 patients with gastric cancer undergoing radical operation in
our hospital from April 2011 to April 2014 were selected as research objects. The patients were divided into two
groups according to the occurrence of FDGE: FDGE group (n=45, patients with FDGE occurred) and non-FDGE
group (n=108, patients without FDGE). Single factor analysis was performed, and then Logistic regression analysis
was performed to analyze the risk factors of FDGE after gastric cancer radical operation. Results The rate of postop-
erative blood glucose > 8 mmol/L, perioperative albumin levels ≤30 g/L, gastric retention before operation, Billroth
Ⅱ type as anastomotic mode, not keeping the vagus nerve trunk, and anxiety in FDGE group were significantly higher
than those in non-FDGE group (all P<0.05). According to Logistic regression analysis, postoperative blood glucose >
8 mmol/L, perioperative albumin levels ≤30 g/L, gastric retention before operation, Billroth Ⅱ type as anastomotic
mode, not keeping the vagus nerve trunk and anxiety were all the risk factors of FDGE after gastric cancer radical op-
eration. Conclusion There are lots of risk factors that influence FDGE after gastric cancer radical operation, which
should be paid attention to in clinic.

      【Key words】 Gastric cancer; Functional gastric emptying disorder; Risk factors; Analysis
基金项目：陕西省教育厅2012自然科学基金科研课题（编号：12JK0707）