标题:三七化瘀口服液对重症脓毒血症患者血流动力学和乳酸值的影响
作者:戚振红 1,陈家鑫 2,马明远 1,马天威 1,张云海 1,苏 懿 1
(1.广州中医药大学附属佛山中医院 ICU,广东 佛山 528000;
2.广东医学院附属禅城医院内科,广东 佛山 528031)
卷次:
2015年26卷7期
【摘要】 目的 探讨三七化瘀口服液对重症脓毒血症患者血流动力学和乳酸值的影响。方法 将80例脓
毒血症患者随机分为观察组和对照组,每组40例。所有患者均给予脓毒血症常规治疗,观察组在此基础上再给
予三七化瘀口服液治疗,7 d为一个疗程。比较两组患者治疗前后的血流动力学、血乳酸浓度、中医症候群积分
和APACHEⅡ评分。结果 治疗后两组患者的血流动力学均显著改善(P<0.01),观察组患者治疗后血流动力学
显著优于对照组(P<0.05)。两组患者治疗后血乳酸浓度均显著降低(P<0.01),观察组患者治疗后各时点均显著低
于对照组(P<0.05)。两组患者治疗后中医症候群积分和APACHEⅡ评分均显著降低(P<0.01),观察组患者治疗后
各时点均显著低于对照组(P<0.05)。结论 三七化瘀口服液能改善低脓毒血症患者血流动力学并降低其血清乳
酸值,改善患者临床症状,具有临床应用价值。
【关键词】 脓毒血症;三七化瘀口服液;血流动力学;血乳酸
【中图分类号】 R631+.2 【文献标识码】 A 【文章编号】 1003—6350(2015)07—0955—03
Influence of notoginseng compound oral liquid on haemodynamics and serum lactate level in patients with
severe sepsis.
QI Zhen-hong 1, CHEN Jia-xin 2, MA Ming-yuan 1, MA Tian-wei 1, ZHANG Yun-hai 1, SU Yi 1.
1. Intensive Care Unit (ICU), Foshan Chinese Traditional Medical Hospital Affiliated to Guangzhou Chinese Traditional
Medical University, Foshan 528000, Guangdong, CHINA; 2. Department of Internal Medicine, Chancheng Hospital
Affiliated to Guangzhou Medical College, Foshan 528031, Guangdong, CHINA
【Abstract】 Objective To study the influence of notoginseng compound oral liquid on haemodynamics and
serum lactate level in patients with severe sepsis. Methods A total of 80 patients with severe sepsis were randomly
divided into study group and control group, with 40 patients in each group. All the patients were treated by routine
therapy, and the patients in study group were additionally treated by notoginseng compound oral liquid, seven days as
a course. The haemodynamics, serum lactate level, TCM syndrome integral score and APACHE Ⅱ score were com-
pared. Results After treatment, the haemodynamics in both groups were significantly improved (P<0.01). The hae-
modynamics in study group was significantly better than that in control group after treatment (P<0.05). After treat-
ment, the serum lactate level in both groups were significantly decreased (P<0.01). The serum lactate level in study
group was significantly lower than that in control group in all time points after treatment (P<0.05). After treatment the
haemodynamics in both groups were significantly improved (P<0.01). The haemodynamics in study group was signifi-
cantly better than that in control group in all time points after treatment (P<0.05). Conclusion Notoginseng com-
pound oral liquid can improve haemodynamics and decrease serum lactate level in patients with severe sepsis, which
makes it worth for clinical application.
下载PDF