标题：腹膜透析相关性葡萄球菌腹膜炎的影响因素分析

      作者：邓金华 1，王定勇 2，汪嘉莉 1，王 松 1
    (1.绵阳市中心医院肾病科，四川 绵阳 621000；
2.绵阳市人民医院泌尿外科，四川 绵阳 621000)

      卷次： 2015年26卷5期

      【摘要】 目的 探讨腹膜透析相关性葡萄球菌腹膜炎的影响因素。方法 回顾性分析250例进行持续性腹
膜透析患者的临床资料，根据是否发生葡萄球菌腹膜透析相关性腹膜炎分为腹膜炎组(28例)与正常组(222例)。
对两组持续性腹膜透析患者的15项可能的影响因素进行方差分析，将筛选出的有统计学意义的影响因素进行多
因素Logistic回归分析，确定腹膜透析相关性葡萄球菌腹膜炎的相关危险因素。结果 两组患者的年龄、性别、
糖尿病肾病、慢性肾炎、糖尿病史、心脏病史、血红蛋白、C-反应蛋白、血清白蛋白以及钙磷乘积比较差异均具有
统计学意义(P<0.05)；经单因素方差分析结果显示，高龄、男性、心脏病史、糖尿病、慢性肾炎、低血红蛋白、高C反
应蛋白、低血清白蛋白、高钙磷乘积是腹膜透析相关性葡萄球菌腹膜炎的相关影响因素；多因素Logistic回归分
析发现，高龄、糖尿病、低血红蛋白、低血清白蛋白是腹膜透析相关性葡萄球菌腹膜炎的危险因素。结论 腹膜
透析相关性葡萄球菌腹膜炎的相关危险因素是高龄、糖尿病、低血红蛋白、低血清白蛋白。

      【关键词】 腹膜透析；葡萄球菌；腹膜炎；影响因素

      【中图分类号】 R656.4+1 【文献标识码】 A 【文章编号】 1003—6350（2015）05—0648—03


Study on the influence factors of peritoneal dialysis-related peritonitis due to Staphylococcus aureus.
DENG
Jin-hua 1, WANG Ding-yong 2, WANG Jia-li 1, WANG Song 1. 1. Department of Nephropathy, Mianyang Central Hospital,
Mianyang 621000, Sichuan, CHINA; 2. Department of Urology, Mianyang People's Hospital, Mianyang 621000,
Sichuan, CHINA

【Abstract】 Objective To explore the influence factors of peritoneal dialysis-related peritonitis caused by
Staphylococcus aureus. Methods The clinical data of 250 patients of continuous peritoneal dialysis were retrospective-
ly analyzed. They were divided into peritonitis group (28 cases) and control group (222 cases) according to occurrence
of peritoneal dialysis-related peritonitis due to Staphylococcus aureus. The 15 possible influence factors of two groups
were investigated by variance analysis, and then the factors of statistical significance were further analyzed by multivari-
ate Logistic regression. The risk factors of peritoneal dialysis-related peritonitis were identified. Results Statistically
significant differences were found between the two groups in age, gender, diabetic nephropathy, chronic nephritis, dia-
betes, heart disease, hemoglobin, C-reactive protein, serum albumin and calcium phosphorus product (P<0.05). The
single factor variance analysis showed that male, age, history of heart disease, diabetes, chronic nephritis, low hemo-
globin, C-reactive protein, low serum albumin, calcium phosphorus product were the related factors of peritoneal dialy-
sis-related peritonitis of Staphylococcus aureus. Multiple factor Logistic regression analysis showed that age, diabetes,
low hemoglobin, low serum albumin were the risk factors of peritoneal dialysis related peritonitis due to Staphylococ-
cus aureus. Conclusion The relative risk factors of peritoneal dialysis-related peritonitis due to Staphylococcus aureus
are advanced age, diabetes, low hemoglobin, and low serum albumin.

      【Key words】 Peritoneal dialysis; Staphylococcus aureus; Peritonitis; Influence factors