标题：两种银敷料在下肢静脉溃疡治疗中应用效果观察

      作者：郭春兰，赵安珍，付向阳
    (三峡大学第一临床医学院宜昌市中心人民医院门诊外科，湖北 宜昌 443003)

      卷次： 2015年26卷2期

      【摘要】 目的 观察两种银敷料用于下肢静脉溃疡治疗的效果，以指导银敷料在伤口治疗中的合理使用。
方法 对入选的75例下肢静脉溃疡患者随机分为观察组和对照组，观察组使用进口的银离子藻酸盐敷料，对照
组使用国产纳米银敷料处理局部溃疡，两组患肢均给予弹力绷带压力治疗，并接受28 d的治疗方案，研究结束时
伤口未愈者选择湿性愈合技术处理至愈合或外科手术治愈。观察治疗7 d、14 d、21 d时溃疡伤口细菌转阴率，研
究结束时溃疡面积愈合率和愈合效果，并于每次处理伤口时观察评价伤口床表现(渗液清除时间、肉芽分级和周
围皮肤状况)。结果 两组伤口面积愈合率平均为(84.66±10.56)%和(67.33±9.44)%，其中，观察组完全愈合8例、
基本愈合17例、有效12例，对照组完全愈合4例、基本愈合11例、有效22例，两组差异均有统计学意义(P<0.05)；
两组伤口细菌转阴率随着时间的延长均增加，28 d时细菌转阴率均达 100%，差异无统计学意义(P>0.05)；随着
治疗时间的增加，两组伤口表现也显著改善，观察组的效果要明显优于对照组，差异有统计学意义(P<0.05)。
结论 两种银敷料均可清除溃疡伤口感染，改善伤口床的表现，促进溃疡愈合，银敷料治疗下肢静脉性溃疡伤口
有效，但银离子藻酸盐敷料的有效性更优越。

      【关键词】 银离子藻酸盐敷料；纳米银敷料；下肢静脉溃疡；疗效

      【中图分类号】 R658.3 【文献标识码】 A 【文章编号】 1003—6350(2015)02—0188—04


Effect of two silver dressings on venous leg ulcer.
GUO Chun-lan, ZHAO An-zhen, FU Xiang-yang. Outpatient
Department of Surgery, the First Clinical Medical College of China Three Gorges University, Yichang Central People's
Hospital, Yichang 443003, Hubei, CHINA

【Abstract】 Objective To observe the effects of two silver dressing in the treatment of venous leg ulcer, and
to guide proper use of silver dressings on wound treatments. Methods Seventy-five patients with venous leg ulcers
were randomly divided into two groups: the observation group and the control group. The observation group was treat-
ed with imported silver ion alginate dressing, and the control group was treated with domestic nanometer silver dress-
ing. Elastic bandages were applied to affect extremities of two groups. The treatment lasted for 28 days. The bacterial
clearance rate of ulcer wound was compared 7 d, 14 d, 21 d after treatment. The performance of the wound bed (fluid
clearance time, granulation grading and the surrounding skin condition) was observed whenever the wound was cared.
The healing rate and effect of ulcer area was evaluated at the end of the research. Results The average healing rate of
·论 著·doi:10.3969/j.issn.1003-6350.2015.02.0066