标题：腹腔镜直肠癌根治术对患者尿动力学及消化道功能状态的影响

      作者：严 海，胡清林
    （成都医学院第一附属医院普外科，四川 成都 617000）

      卷次： 2015年26卷1期

      【摘要】 目的 观察腹腔镜直肠癌根治术后患者尿动力学及消化道功能状态的变化。方法 选取2011年9
月至2014年1月于本院进行根治性手术治疗的74例直肠癌患者为研究对象，将其随机分为对照组(开腹手术组)
和观察组(腹腔镜手术组)各37例，检测并比较两组患者手术前后的尿动力学变化及血清胃肠激素和小肠传输功
能。结果 观察组手术后3 d及7 d的尿动力学指标最大尿流率、最大排尿压及排尿期逼尿肌收缩压均大于对照
组，残余尿量则小于对照组，血清胃肠激素GAS、MTL、VIP、SS水平均高于对照组，以上指标比较差异均有统计
学意义(P<0.05)；术后1 d及3 d的小肠传输功能相关指标AUC及PC显著高于对照组，PT低于对照组，差异均有
统计学意义(P<0.05)。结论 腹腔镜直肠癌根治术对患者尿动力学及消化道功能状态的不良影响明显小于开腹
手术患者，且患者术后的上述各项指标恢复相对较快。

      【关键词】 腹腔镜直肠癌根治术；尿动力学；消化道功能

      【中图分类号】 R735.3+7 【文献标识码】 A 【文章编号】 1003—6350（2015）01—0025—03


Influence of laparoscopic radical resection of rectal cancer on the urodynamics and digestive tract function of
patients.
YAN Hai, HU Qing-lin. Department of General Surgery, the First Affiliated Hospital of Chengdu Medical
School, Chengdu 617000, Sichuan, CHINA

【Abstract】 Objective To observe the changes in the urodynamics and digestive tract function of patients af-
ter laparoscopic radical resection of rectal cancer. Methods Seventy-four patients with rectal cancer in our hospital
from September 2011 to January 2014 were selected as study subjects, which were randomly divided into control
group (open operation group, n=37) and observation group (laparoscopic operation group, n=37). Then the urodynam-
ic changes, serum gastrointestinal hormones, and small intestine transmission function of two groups before and after
the operation were detected and compared. Results 3 d and 7 d after operation, the urodynamic indices such as maxi-
mum flow rate, maximum voiding detrusor voiding pressure and systolic blood pressure of the observation group were
significantly greater than control group, while the residual urine volume was significantly less than the control group,
and the serum levels of gastrointestinal hormone such as GAS, MTL, VIP, SS levels were significantly higher than the
control group, P<0.05. 1 d and 3 d after operation, intestinal transport functions related indicators (AUC and PC) were
significantly higher control group, and PT was significantly lower than the control group, P<0.05. Conclusion The
bad influence of laparoscopic radical resection of rectal cancer on the urodynamics and digestive tract function of pa-
tients are significantly smaller than that of open operation, with relatively rapid recovery of the related indices.