标题：糖化血红蛋白与空腹血糖检测在糖尿病临床诊疗中的应用

      作者：朱红霞，李 英，王敏哲
    (新疆医科大学第五附属医院内分泌科，新疆 乌鲁木齐 830011)

      卷次： 2014年25卷13期

      【摘要】 目的 对比研究糖化血红蛋白(HbA1c)与空腹血糖(FPG)检测在糖尿病临床诊疗中的应用效果。
方法 随机选取我院收治的糖尿病患者 46例，设定为实验组，同时随机选取正常体检者 46例，设定为对照组。
测定两组受试人员的HbA1c和FPG指标，比较其差异并分析其结果。结果 实验组平均HbA1c为(9.19±1.76)%，对
照组仅为(5.14±0.99)%，实验组平均 FPG含量为(10.34±3.57) mmol/L，对照组仅为(4.98±2.21) mmol/L，其差异
均具有统计学意义(P<0.05)。HbA1c与 FPG呈正相关关系。HbA1c介于 4.0%~5.9%者 FPG的浓度仅为(4.47±
1.97) mmol/L；HbA1c介于6.0%~6.9%者FPG的浓度为(5.02±2.35) mmol/L；HbA1c介于7.0%~7.9 %者FPG的浓度为
(7.65±2.77) mmol/L；而HbA1c介于 8.0%~8.9%者 FPG浓度高达(9.89±3.01) mmol/L。大于 9.0%者 FPG浓度高达
(11.41±3.74) mmol/L。结论 糖化血红蛋白和空腹血糖均是糖尿病诊疗的重要指标。FPG为最常用的检测糖尿
病方法，简便易行但是可能出现误诊；HbA1c为高效且准确的检测糖尿病方法，而且不易受干扰；HbA1c和FPG呈
正相关，综合分析这些指标在诊疗糖尿病时效果更好。

      【关键词】 糖化血红蛋白；空腹血糖；糖尿病；综合效果；对比

      【中图分类号】 R587.1 【文献标识码】 A 【文章编号】 1003—6350（2014）13—1956—03


Effects of haemoglobin A1c and fasting plasma glucose in clinical diagnosis and treatment of diabetes.
ZHU
Hong-xia, LI Ying, WANG Min-zhe. Department of Endocrinology, the Fifth Affiliated Hospital of Xinjiang Medical
University, Urumchi 830011, Xinjiang, CHINA

【Abstract】 Objective To compare and study the comprehensive effects of haemoglobin A1c and fasting plas-
ma glucose in diagnosis and treatment of diabetes. Methods Forty-six cases of diabetes patients in our hospital from
April 2010 to April 2012 were selected as experimental group, while another 46 cases of healthy people were selected
as control group. The HbA1c and FPG in both two groups were measured and analyzed. Results The average value of
HbA1c in experimental group was (9.19±1.76)%, while it was only (5.14±0.99) % in control group. The average val-
ue of FPG was (10.34±3.57) mmol/L in experimental group and (4.98±2.21) mmol/L in control group. Both the dif-
ferences were statistically significant. There was positive correlation between HbA1c and FPG. When HbA1c were in
the range of (4.0%~5.9%, 6.0%~6.9%, 7.0%~7.9%, 8.0%~8.9%, and greater than 9.0%, the value of FPG were
(4.47±1.97) mmol/L, (5.02±2.35) mmol/L, (7.65±2.77) mmol/L, (9.89±3.01) mmol/L and (11.41±3.74) mmol/L re-
spectively. Conclusion Both HbA1c and FPG are important indexes in diagnosing and treating diabetes. FPG is the
most common method for detecting diabetes, which is easy to be performed but trend to misdiagnosis, while HbA1c is
efficient and accurate in detecting diabetes with less disturbance. Since there is a positive correlation between these two
indexes, a combination analysis of them for diagnosis and treatment of diabetes shows more advantages.

      【Key words】 Haemoglobin A1c (HbA1c)；Fasting plasma glucose (FPG)；Diabetes; General effects; Compare
·论 著·