标题：水化对肾灌注造影患者造影剂肾病的影响

      作者：刘春斌 1，李 凯 2
    (1.广西卫生职业技术学院，广西 南宁 530021；
2.广西医科大学第一附属医院，广西 南宁 530021)

      卷次： 2014年25卷7期

      【摘要】 目的 观察水化对冠状动脉造影患者肾功能的影响。方法 收集2011年9月至2013年8月2型
糖尿病（T2DM）患者25例，应用低渗非离子型造影剂进行肾灌注造影，造影前及造影后第1、3天分别测定患者的
血葡萄糖、24 h尿微量白蛋白、24 h尿蛋白定量、血尿素氮、血肌酐等各项指标，评价造影剂肾病的发生情况及肾
功能的变化情况。结果 T2DM患者灌注造影后均未发生CIN。造影灌注后第1、3天24 h微量白蛋白、24 h蛋
白定量、血尿素氮、血肌酐与造影前比较差异均无统计学意义(P>0.05)。结论 加强水化能减轻肾功能伤害，减
少造影剂肾病的发生率。

      【关键词】 水化；造影剂肾病；灌注成像

      【中图分类号】 R692 【文献标识码】 A 【文章编号】 1003—6350（2014）07—0962—02


Effect of hydration in prevention of contrast-induced nephropathy after renal perfusion imaging.
LIU Chun-bin 1,
LI Kai 2. 1. Gangxi Medical College, Nanning 530021, Guangxi, CHINA; 2. The First Affiliated Hospital of Guangxi
Medical University, Nanning 530021, Guangxi, CHINA

【Abstract】 Objective To observe the effects of hydration on renal function in patients undergoing renal per-
fusion imaging. Methods Twenty-five patients of type 2 diabetes mellitus (T2DM) admitted into our hospital from
Sep. 2011 to Aug. 2013 were recruited in this study. The low osmolar and nonionic contrast media was used in all pa-
tients. The blood glucose, 24 h urinary albumin, 24 h urinary protein, blood urea nitrogen, creatinine and other indica-
tors of the patients were detected before imaging, 1 day and 3 days after imaging. The incidence of contrast-induced
nephropathy and renal function changes were evaluated. Results No patient suffered contrast-induced nephropathy
(CIN) after perfusion imaging. The 24 h urinary albumin, 24 h urinary protein, blood urea nitrogen and creatinine
didn't have significant changes before imaging, 1 day and 3 days after imaging (P>0.05). Conclusion The strength-
ened hydration therapy can reduce the renal damage and effectively prevent contrast-induced nephropathy.

      【Key words】 Hydration; Contrast-induced nephropathy; Perfusion imaging
·论 著·