标题：海南产沉香挥发油成分研究

      作者：林娜 1，陈静 1，张万科 2，易博 1
    (1.中国人民解放军第一八七医院药剂科，海南 海口 571159；
2.海南医学院药学院，海南 海口 571199)

      卷次： 2016年27卷9期

      【摘要】 目的 对海南产沉香挥发油的成分进行研究。方法 采用低温-动态-微波法及气相色谱-质谱
(GC-MS)联用技术，以固相微萃取顶空进样，提取并分析国产沉香挥发油中的化学成分。结果 从海南产沉香样
品挥发油中检出54种化合物，占总峰面积的43.23%，主要为倍半萜类、芳香族和脂肪酸类化合物。其中倍半萜类
化合物检出26个，相对总含量达36.87%，尤以β-瑟林烯和沉香螺旋醇含量较高，分别为6.47%和4.63%。结论 海
南产沉香挥发油中的倍半萜成分丰富，可为进一步质量控制研究提供参考。

      【关键词】 沉香；挥发油；气相色谱-质谱联用技术；固相微萃取

      【中图分类号】 R282.71 【文献标识码】 A 【文章编号】 1003—6350（2016）09—1383—03


Study on volatile oil components from Lignum Aquilariae Resinatum produced in Hainan.
LIN Na 1, CHEN Jing 1 ,
ZHANG Wan-ke 2, YI Bo 1. 1. Department of Pharmacy, the 187th General Hospital of People's Liberation Army, Haikou
571159, Hainan, CHINA; 2. Hainan Medical University, Haikou 571199, Hainan, CHINA

【Abstract】 Objective To analyze the volatile oil components from Lignum Aquilariae Resinatum produced in
Hainan. Methods The volatile components were extracted by low temperature-dynamic microwave method and gas
chromatography-mass spectrometry (GC-MS) technique, with solid-phase microextraction (SPME) for head-space injec-
tion. The constituents in volatile oil were analyzed. Results Fifty-four compounds were detected and identified from
the agarwood sample, representing 43.23% of the total volatile oil. The compounds mainly included ingredients like es-
quiterpenes, benzene compounds and fatty acids. Twenty-six esquiterpenes have been identified and the total relative con-
tents accounted for 36.87%, mainly β-selinene (6.47%) and agarospirod (4.63%). Conclusion The volatile oil of agar-
wood sample produced in Hainan contains rich esquiterpenes.

      【Key words】 Lignum Aquilariae Resinatum; Volatile oil; Gas chromatography-mass spectrometry (GC-MS); Sol-
id-phase microextraction (SPME)
·论 著·
6350.2016.09.002