标题：早期肠内营养对重症急性胰腺炎患者机体综合状态的影响

      作者：杨宁梅 1，申艳玲 2，王 丽 1，李雪梅 1
    (1.南充市中心医院重症医学科，四川 南充 637000；
2.北京中日友好医院重症医学科，北京 100029)

      卷次： 2013年24卷24期

      【摘要】 目的 探讨早期肠内营养对重症急性胰腺炎患者机体综合状态的影响。方法 选取2010年1月
至2012年12月于南充市中心医院进行治疗的96例重症急性胰腺炎患者为研究对象，将其随机分为对照组48例
和观察组48例，对照组采用全胃肠外营养支持，观察组则采用早期肠内营养支持，将两组患者干预前与干预后1
周、2周的免疫状态指标、营养状态指标及炎性状态指标进行比较。结果 观察组干预后1周、2周的免疫状态指
标、营养状态指标及炎性状态指标均显著优于对照组，对照组干预后2周明显优于干预前，差异均有统计学意义
(P<0.05)。结论 早期肠内营养对重症急性胰腺炎患者机体综合状态的影响更为积极，有助于控制患者的炎性
状态及调整机体免疫、营养状态。

      【关键词】 早期肠内营养；重症急性胰腺炎；机体综合状态；影响

      【中图分类号】 R657.5+1 【文献标识码】 A 【文章编号】 1003—6350（2013）24—3616—03


Influence of early enteral nutrition for the body comprehensive state of patients with severe acute pancreatitis.
YANG Ning-mei 1, SHEN Yan-ling 2, WANG Li 1, LI Xue-mei 1.
1. Department of ICU, Central Hospital of Nanchong,
Nanchong 637000, Sichuan, CHINA; 2. Department of ICU, Beijing China-Japan Friendship Hospital, Beijing 100029,
CHINA

【Abstract】 Objective To study the influence of early enteral nutrition for the body comprehensive state of
patients with severe acute pancreatitis. Methods A total of 96 patients with severe acute pancreatitis from January
2010 to December 2012 were selected and randomly divided into control group (48 cases) and observation group (48
cases).and Patients in the control group were intervened with total parenteral nutrition support，and patients in the ob-
servation group were intervened with early enteral nutrition support. The immune state indexes，nutritional state index-
es and inflammatory state indexes of two groups before the intervention and at 1st，2nd week after the intervention were
compared. Results The immune state indexes，nutritional state indexes and inflammatory state indexes in observa-
tion group at 1st and 2nd week after the intervention were all significantly better than those in control group，those index-
es of observation group at 2nd week after the intervention were obviously better than those before the intervention, all
with P<0.05. Conclusion The influence of early enteral nutrition is more active for the body comprehensive state of
patients with severe acute pancreatitis，which is helpful for controlling of inflammatory state and adjusting of immune
state and nutritional state.

      【Key words】 Early enteral nutrition; Severe acute pancreatitis; Body comprehensive state; Influence