标题：肥胖患者营养与行为干预研究

      作者：刘 芳，蒋一倩，马志红，周桂英
    (上海市松江区中心医院营养科，上海 201600)

      卷次： 2013年24卷21期

      【摘要】 目的 探索和评价营养和行为干预对肥胖患者体重及生化指标的影响。方法 选取本院体检中
心100名肥胖患者，检测体重、身高、腰围、臀围、血压(BP)并计算身体质量指数(BMI)和腰臀比；同时采集研究对
象血样，检测三酰甘油(TG)、胆固醇(TC)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、血糖
(FPG)和血尿酸(UA)。进一步通过单纯随机抽样选取50例，一对一进行营养知识行为指导，进行合理膳食结构调
整及改变不良生活方式。50例对照组仅给予医学对症处理，干预时间为1年，之后重新测定患者体重及生化指
标。结果 干预组干预后，BMI (P<0.001)、TG (P<0.001)、TC (P=0.036<0.05)、LDL-C (P=0.001<0.05)、FPG (P=
0.006<0.05)和UA (P<0.001)均较干预前下降，而对照组干预后各指标与干预前比较差异无统计学意义；干预后，
干预组舒张压(P=0.02<0.05)三酰甘油(P<0.001)、胆固醇(P<0.001)、高密度脂蛋白胆固醇(P<0.001)、低密度脂蛋白胆
固醇(P<0.001)、血糖(P<0.001)均低于对照组。结论 合理的营养和行为干预是改善肥胖患者体质的有效方式。

      【关键词】 肥胖患者；营养; 行为；干预

      【中图分类号】 R459.3 【文献标识码】 A 【文章编号】 1003—6350（2013）21—3164—04


Study of nutrition and behavior intervention on obese patients.
LIU Fang, JIANG Yi-qian, MA Zhi-hong, ZHOU
Gui-ying. Department of Nutrition, the Central Hospital of Songjiang District of Shanghai, Shanghai 201600, CHINA

【Abstract】 Objective To explore and evaluate the effect of nutrition and behavior intervention on obese pa-
tients. Methods One hundred obese male patients were randomly selected in the Central Hospital of Songjiang Dis-
trict of Shanghai. Body weight, height, waist-hip circumference, and blood pressure of the patients were measured,
and body mass index (BMI) and waist-hip ratio were calculated. Blood samples were collected, and serum triglyceride
(TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol
(LDL-C), fasting plasma glucose (FPG) and serum uric acid (UA) were measured before intervention. Fifty of the 100
patients were randomly selected as the intervention group, which were given face-to-face instructions on correcting
the unhealthy behaviors, the eating habits as nutrition and behavior intervention therapy. Symptomatic treatment was al-
so applied. The other 50 patients (the control group) were treated based on symptoms only. Body condition and blood
biochemical parameters were measured again after one year of follow-up. Results BMI (P<0.001), TG (P<0.001), TC
(P=0.036<0.05), LDL-C (P=0.001<0.05), FPG (P=0.006<0.05) and UA (P<0.001) were significantly lower after inter-
vention in the intervention group, while no significant difference was found in the indexes after intervention in the
control group (P<0.05). There were statistically significant differences in diastolic blood pressure (P=0.02<0.05),
TC (P<0.001), TG (P<0.001), HDL-C (P<0.001), LDL-C (P<0.001), FPG (P<0.001) between the two groups after in-
tervention. Conclusion Nutrition and behavior intervention can effectively decrease BMI, serum lipid, the glucose,
blood pressure, and serum uric acid of obese patients.

      【Key words】 Obesity; Nutrition; Behavior; Intervention
·论 著·