标题：延安地区被误诊哮喘患儿发病危险因素的变化探讨

      作者：冯 娜，李元霞，张慧平，庞随军
    （延安大学附属医院儿科一病区，陕西 延安 716000）

      卷次： 2013年24卷20期

      【摘要】 目的 分析12年来延安地区被误诊的哮喘患儿的发病危险因素的变化情况，为本区儿童哮喘的诊
断及治疗提供参考。方法 选择2000年1月至2011年12月在延安大学附属医院确诊被误诊的哮喘患儿148例，
选择148名年龄和性别匹配的健康儿童为对照。利用Logistic回归分析查找被误诊的哮喘患儿的发病相关危险
因素。结果 2000年1月至2003年12月被误诊的哮喘患儿的发病主要影响因素为细菌感染、哮喘家族史、个人
过敏史、气候变化。2004年1月至2007年12月被误诊的哮喘患儿的发病主要影响因素为环境因素、细菌、病毒
混合感染、哮喘家族史以及个人过敏史。2008年1月至2011年12月被误诊的哮喘患儿的发病主要影响因素包括
病毒感染、支原体感染、肥胖、环境因素、哮喘家族史、个人过敏史。结论 被误诊的哮喘患儿的发病危险因素逐
渐变化，病毒、支原体感染以及单纯性肥胖逐渐成为诱发儿童哮喘的新的主要危险因素。

      【关键词】 儿童；哮喘；误诊；危险因素

      【中图分类号】 R725.6 【文献标识码】 A 【文章编号】 1003—6350（2013）20—3011—03


Changes in risk factors of asthma in misdiagnosed children over the past 12 years in Yan'an region.
FENG Na,
LI Yuan-xia, ZHANG Hui-ping, PANG Sui-jun. Ward One, Department of Pediatrics, the Affiliated Hospital of Yan'an
University, Yan'an 716000, Shaanxi, CHINA

【Abstract】 Objective To analyze the changes in risk factors of asthma in children patients who had been
misdiagnosed in the recent 12 years in Yan'an, and to provide a new diagnostic and therapeutic ideas of childhood asth-
ma. Methods A total of 148 children with asthma who had been misdiagnosed from January 2000 to December 2011
were treated as subjects. At the same time, 148 age and sex-matched children without asthma were chosen as the con-
trol group. Multiple logistic regression analysis was used to identify risk factors for asthma in children patients who
had been misdiagnosed. Results From January 2000 to December 2003, the risk factors of asthma in children pa-
tients who had been misdiagnosed were bacterial infection, family history of asthma, personal history of allergy, and
climate Change. From January 2004 to December 2007, the risk factors of asthma in children patients who had been
misdiagnosed were environmental factors, mixed infection of bacteria and viruses, family history of asthma, and per-
sonal history of allergy. From January 2008 to December 2011, the risk factors of asthma in children patients who had
been misdiagnosed were virus infection, mycoplasma infection, simple obesity, environmental factors, family history
of asthma, and personal history of allergy. Conclusion The risk factors of asthma in children patients who had been
misdiagnosed are gradually changing. Virus infection, mycoplasma infection, and simple obesity are becoming major
risk factors related to childhood asthma.

      【Key words】 Children; Asthma; Misdiagnosis; Risk factors