标题：AIDS孕妇母婴阻断前后血清主要生化指标的变化

      作者：杨翠娟 1，苏国生 2*，磨立达 2
    (1.百色市右江区人民医院检验科，广西 百色 533000；
2.南宁市第四人民医院检验科 广西医科大学附属南宁市传染病医院
广西艾滋病临床治疗中心，广西 南宁 530023)

      卷次： 2016年27卷8期

      【摘要】 目的 探讨艾滋病(AIDS)孕妇患者母婴阻断前后主要生化指标的变化情况。方法 选取 2013年
1月至 2015年 6月在本院收治并进行母婴阻断的AIDS孕妇患者 152例，治疗前后检测血清双感生化项目，观
察各指标的变化情况。结果 152例AIDS孕妇患者中，母婴阻断前血清氯离子、乳酸、直接胆红素检测结果
分别为(100.66±3.39) mmol/L、(3.08±1.42) mmol/L、(4.09±4.68) ?mol/L，而阻断后分别为(101.51±3.24) mmol/L、
(2.58±1.20) mmol/L、(3.37±2.48) ?mol/L，阻断前后比较差异均具有统计学意义(P<0.05)，其他指标检测结果比较差异
均无统计学意义(P>0.05)。结论 AIDS孕妇母婴阻断前后主要生化指标总体上变化不大，仅有氯离子、乳酸及直接
胆红素变化较大，临床治疗可根据其变化情况，观察机体所处的状态，对及时调整用药方案具有重要的现实意义。

      【关键词】 艾滋病；孕妇；母婴阻断；生化指标

      【中图分类号】 R512.91 【文献标识码】 A 【文章编号】 1003—6350（2016）08—1255—03


Changes of main biochemical parameters of serum before and after interruption of mother-infant transmission
in AIDS pregnant women.
YANG Cui-juan 1, SU Guo-sheng 2*, MO Li-da 2. 1. Youjiang District People's Hospital of
Baise City, Baise 533000, Guangxi, CHINA; 2. Clinical Laboratory, the Fourth People's Hospital of Nanning (the Nanning
Infectious Diseases Affiliated Hospital of Guangxi Medical University, Guangxi AIDS Clinical Treatment Center), Nanning
530023, Guangxi, CHINA

【Abstract】 Objective To investigate changes of main biochemical parameters of serum before and after inter-
ruption of mother-infant transmission in AIDS pregnant women. Methods From January 2013 to June 2015, a total of
152 AIDS pregnant patients were enrolled in the study in our hospital, and changes of main biochemical parameters of se-
rum before and after interruption of mother-infant transmission in AIDS pregnant women were detected. Results The lev-
els of chloride, lactic acid and direct bilirubin before interruption of mother-infant transmission [(100.66±3.39) mmol/L,
(3.08±1.42) mmol/L and (4.09±4.68) ?mol/L, respectively] were lower than those after treatment [(101.51±3.24) mmol/L,
(2.58±1.20) mmol/L and (3.37±2.48) ?mol/L, respectively], and there were statistically significant differences before
and after the interruption (t=2.2348, 3.3157 and 1.676 respectively, P<0.05). There was no statistically significant differ-
ence in other indicators before and after interruption. Conclusion In addition to the chloride, lactic acid and direct bil-
irubin, the main biochemical parameters of AIDS pregnant women did not change significantly before and after before
and after interruption of mother-infant transmission. Observing the state of the bodies will be helpful to adjust medica-
tion plans timely.

      【Key words】 AIDS; Pregnant women; Interruption of mother-infant transmission; Biochemical indicators
·论 著·
6350.2016.08.016