标题：老年高血压患者血压变异与颈动脉斑块的相关性研究

      作者：郑才 1，周敏芳 2，邓峰 3，黎绮霞 4
    (1.佛山市禅城区向阳医院西医科门诊，广东 佛山 528000；
2.广州武警医院急诊科，广东 广州 510507；
3.佛山市禅城区向阳医院家床科，广东 佛山 528000；
4.佛山市南海区许海中学医务室，广东 佛山 528000)

      卷次： 2016年27卷8期

      【摘要】 目的 探讨老年高血压患者血压变异与颈动脉斑块的关系。方法 选择2014年12月至2015年5月
间我院诊治的90例高血压患者作为研究对象，根据是否合并颈动脉斑块将患者纳入斑块组(n=63)及无斑块组(n=
27)，比较两组患者血脂及血压变异性。结果 斑块组患者血甘油三脂(TG)、总胆固醇(TC)及低密度脂蛋白胆固醇
(LDL-C)分别为(2.9±1.2) mmol/L、(5.9±1.3) mmol/L、(3.9±0.9) mmol/L，均明显高于无斑块组的(2.3±1.1) mmol/L、
(5.3±1.2) mmol/L、(3.5±0.8) mmol/L，差异均有统计学意义(P<0.05)；斑块组患者24 h收缩压变异、24 h舒张压变异、
白昼收缩压变异、白昼舒张压变异分别为(13.3±3.2)%、(12.4±3.3)%、(11.7±2.9)%、(11.1±3.1)%，均明显高于无斑块组的
(9.8±2.9)%、(10.1±2.7)%、(9.6±1.8)%、(8.9±2.8)%，差异均有统计学意义(P<0.05)；两组患者夜间收缩压变异、夜间舒张
压变异比较差异均无统计学意义(P>0.05)。结论 老年高血压患者颈动脉斑块的发生与血压变异性密切相关。

      【关键词】 老年；高血压；动脉粥样硬化；血压变异；相关性

      【中图分类号】 R544.1 【文献标识码】 A 【文章编号】 1003—6350（2016）08—1217—02


Association between blood pressure variability and carotid artery plaque in elderly patients with hypertension.
ZHENG Cai 1, ZHOU Min-fang 2, DENG Feng 3, LI Qi-xia 4.
1. Department of West Medical Clinic, Chancheng District
Xiangyang Hospital of Foshan City, Foshan 528000, Guangdong, CHINA; 2. Department of Emergency, Guangzhou Armed
Police Hospital, Guangzhou 510507, Guangdong, CHINA; 3. Department of Family Bed, Chancheng District Xiangyang
Hospital of Foshan City, Foshan 528000, Guangdong, CHINA; 4. Clinic, Xu Hai Middle School in the South Sea District of
Foshan City, Foshan 528000, Guangdong, CHINA

【Abstract】 Objective To investigate the relationship between blood pressure variability and carotid artery plaque
in elderly patients with hypertension. Methods From December 2014 to May 2015, 90 elderly patients with hypertension
in our hospital were grouped into the plaque group (n=63) and no plaque group (n=27) according to whether the patients
had carotid artery plaque. Blood lipid and blood pressure variability were compared between two groups. Results The
blood TG, TC and LDL in the plaque group [(2.9±1.2) mmol/L, (5.9±1.3) mmol/L and (3.9±0.9) mmol/L] were significant-
ly higher than in the no plaque group [(2.3±1.1) mmol/L, (5.3±1.2) mmol/L and (3.5±0.8) mmol/L], and the differences be-
tween two groups were statistically significant (P<0.05). The 24 h systolic blood pressue variation (SBPV), 24 h diastolic
blood pressue variation (DBPV), day SBPV (dSBPV) and day DBPV (dDBPV) in the plaque group [(13.3±3.2)%, (12.4±
3.3)%, (11.7±2.9)% and (11.1±3.1)%] were significantly higher than in the no plaque group [(9.8±2.9)%, (10.1±2.7)%,
(9.6±1.8)% and (8.9±2.8)%], and the differences were statistically significant (P<0.05). There were no significant differ-
ence between two groups in the night SBPV (nSBPV) and night DBPV (nDBPV), P>0.05. Conclusion The occurrence
of carotid plaque in elderly patients with hypertension is closely related to blood pressure variability.

      【Key words】 Elderly; Hypertension; Atherosclerosis; Blood pressure variability; Correlation
·论 著·
6350.2016.08.003