标题：数字减影CT灌注成像在股骨头早期缺血性坏死中的应用

      作者：刘海明，梁辉清，刘万新，刘日新，黄锦钊，袁国奇
    (广东医学院附属陈星海医院放射科，广东 中山 528415)

      卷次： 2013年24卷16期

      【摘要】 目的 探讨数字减影CT灌注成像(Subtraction CT perfusion imaging，SCTP)在股骨头早期缺血坏死
(Avascular necrosis of femoral head，ANFH)中的应用。方法 股骨头早期缺血性坏死19例，股骨头灌注前先行平
扫，再进行同层面灌注扫描，将灌注图像经数字减影后得到一组新灌注图像。再经工作站灌注软件后处理，计算
出血流量(BF)、血容量(BV)、对比剂平均通过时间(MTT)及相应色阶图，用于ANFH诊断。结果 早期ANFH患
侧(27侧)股骨头BF数值较健侧(11侧) BF显著减少，差异有统计学意义(P<0.05)。患侧股骨头BV、MTT数值对
比健侧组间差异无统计学意义(P>0.05)。结论 SCTP计算出的BF、BV、MTT能反映早期股骨头缺血的微循环
灌注信息，可以为临床诊断ANFH提供重要的诊断依据。

      【关键词】 灌注成像；数字减影；股骨头坏死；X线计算机体层摄影术

      【中图分类号】 R445 【文献标识码】 A 【文章编号】 1003—6350（2013）16—2396—03


Application of subtraction CT perfusion imaging in early avascular necrosis of femoral head.
LIU Hai-ming,
LIANG Hui-qing, LIU Wan-Xin, LIU Ri-xin, HUANG Jin-zhao, YUAN Guo-qi. Department of Radiology, Chenxinghai
Hospital Affiliated to Guangdong Medical College, Zhongshan 528415, Guangdong, CHINA

【Abstract】 Objective To investigate the application of subtraction CT perfusion imaging (SCTP) in early
avascular necrosis of femoral head (ANFH). Methods Nineteen patients of ANFH were performed plain CT scan before
the perfusion, and then performed perfusion scan at the same levels. The perfusion images were processed by digital sub-
traction perfusion software to get a group of new perfusion images. Then the images were post-processed by workstation
perfusion software, and blood flow (BF), blood volume (BV), mean transit time (MTT) and the corresponding color map-
ping were calculated for the diagnosis of ANFH. Results The BF value of femoral head at the affected side of early AN-
FH (n=27) were significantly reduced, compared with that at the healthy side (n=11), P<0.05. There were no statistically
significant differences in BV or MTT between the two sides (P>0.05). Conclusion BF, BV, MTT can demonstrate the mi-
crocirculation perfusion information of ANFH, which provides an important basis for the clinical diagnosis of ANFH.

      【Key words】 Perfusion imaging; Digital subtraction; Necrosis of femoral head; X-ray computed tomography
·论 著·