标题：整合素在前列腺癌中的作用

      作者：卓小岸 1 综述，陈化磊 2 审校
    （1.海南省人民医院急诊科，海南 海口 570311；
2.海南省农垦总医院泌尿外科，海南 海口 570311）

      卷次： 2013年24卷13期

      【摘要】 整合素是一类重要的细胞表面受体，通过识别细胞外基质介导细胞间粘附反应，并接受传导级连
信号调节细胞的增殖、运动等生物过程。其在前列腺癌发生、发展中起着重要作用，进一步探讨整合素与前列腺
癌的关系具有重要的临床应用价值。

      【关键词】 整合素；前列腺癌；转移

      【中图分类号】 R737.25 【文献标识码】 A 【文章编号】 1003—6350（2013）13—1964—03


Role of integrin in prostate cancer.
ZHUO Xiao-an 1, CHEN Hua-lei 2. 1. Department of Emergency, People's Hospital
of Hainan Province, Haikou 570311, Hainan, CHINA; 2. Department of Urology, Hainan Provincial Nong Ken Hospital,
Haikou 570311, Hainan, CHINA
【Abstract】 Integrin, a kind of important cell surface receptors, regulates cell proliferation, movements and
other biological proliferation by identifying the extracellular matrix mediated between cells and accept the adhesion of
conduction cascade signal. It plays an important role in the occurrence and development of prostate cancer. Further
study of the integrin and prostate cancer relationship has important value in clinical practice.

      【Key words】 Integrin; Prostatic carcinoma; Metastasis