标题：创伤性脑损伤后睡眠障碍研究进展

      作者：王德玺 1 综述，刘 红 2，张宗平 3 审校
    （1.广东医学院，广东 湛江 524002；
2.四川大学华西医院睡眠医学中心，四川 成都 610041；
3.广东医学院附属湛江肿瘤医院神经外科，广东 湛江 524002)

      卷次： 2013年24卷13期

      【摘要】 睡眠障碍在创伤性颅脑损伤(Traumatic brain injury，TBI)患者中的发生率明显高于社区。TBI后
睡眠障碍主要包括了睡眠呼吸障碍(Sleep-disorder breathing，SDB)、日间过度嗜睡(Excessive daytime sleepiness，
EDS)和失眠等。睡眠障碍常对认知力、警觉性和判断力产生不利影响。在伴有睡眠障碍的创伤性颅脑损伤患者
中，紊乱的睡眠会加重认知功能的损伤，降低患者的生活质量，影响患者的康复。睡眠障碍的常规治疗对伴有睡
眠障碍的TBI患者是有效的，其中包括针对SDB使用的持续气道正压通气(Continuous positive airway pressure，
CPAP)和在失眠患者中的认知行为治疗等。

      【关键词】 创伤性颅脑损伤；睡眠；睡眠障碍

      【中图分类号】 R651.1+5 【文献标识码】 A 【文章编号】 1003—6350（2013）13—1961—03


Research progress on traumatic brain injury and sleep disorders.
WANG De-xi 1, LIU Hong 2, ZHANG Zong-ping 2.
1. Guangdong Medical College, Zhanjiang 524002, Guangdong, CHINA; 2. Sleep Medicine Center, West China Hospital
of Sichuan University, Chengdu 610041, Sichuan, CHINA; 3. Department of Neurosurgery, the Affiliated Zhanjiang Tumor
Hospital of Guangdong Medical College, Zhanjiang 524002, Guangdong, CHINA
【Abstract】 Sleep disorder is common after traumatic brain injury (TBI), including sleep-disorder breathing
(SDB), excessive daytime sleepiness (EDS), and insomnia. Poor sleep can have adverse impacts on cognition, atten-
tion, and judgment. In patients with TBI, disrupted sleep has been shown to impair rehabilitation efforts and progres-
sion, and is associated with diminished quality of life measures. The treatment of TBI-related sleep disorders is the
same as for uninjured patients and includes the use of medications, continuous positive airway pressure (CPAP), or be-
havioral modifications.