标题：糖尿病肾病患者尿微量白蛋白检测的临床意义

      作者：郑 红
    (资阳市第一人民医院检验科，四川 资阳 641300)

      卷次： 2013年24卷13期

      【摘要】 目的 探讨临床上检测尿微量白蛋白对糖尿病肾病(Diabetic nephropathy，DN)患者早期诊断
的意义。方法 采集标本，运用放射免疫方法，检测90例DN患者(研究组)的尿微量白蛋白含量，并与80例健康
体检者(对照组)比较。结果 研究组的尿微量白蛋白含量为(56.74 ± 5.87) mg/L，明显高于正常对照组的
(11.26±3.75) mg/L，两组比较差异有统计学意义(P＜0.05)。不同性别患者尿微量白蛋白比较，差异无统计学意
义(P＞0.05)。不同病程患者的尿微量白蛋白含量比较，差异有统计学意义(P＜0.05)。结论 对糖尿病肾病患者
早期进行尿微量白蛋白检测有助于早期判断糖尿病肾脏的损害，对糖尿病肾病患者早期发现、诊断和治疗具有
重要价值。

      【关键词】 尿微量白蛋白；糖尿病肾病；检测；诊断

      【中图分类号】 R587.2 【文献标识码】 A 【文章编号】 1003—6350（2013）13—1958—03


Clinical significance of urinary microalbumin detection in patients with diabetic nephropathy.
ZHENG Hong.
Department of Clinical Laboratory, Ziyang First People's Hospital, Ziyang 641300, Sichuan, CHINA

【Abstract】 Objective To investigate the clinical value and significance of urinary microalbumin detection for the
early diagnosis in patients with diabetic nephropathy. Methods By radioimmunoassay, urinary microalbumin content
were detected in 90 patients with diabetic nephropathy (the study group) and 80 healthy individuals (the control group).
Results Urinary albumin content of the study group was (56.74±5.87) mg/L, which was significantly higher than that of
the control group [(11.26±3.75) mg/L]. The difference was statistically significant (P<0.05). The difference in urinary mi-
croalbumin between different genders was not statistically significant (P>0.05), while the difference of urinary albumin
content between different course of patients was statistically significant (P<0.05). Conclusion The urine microalbumin
detection can be used as sensitive indicators for the early diagnosis of diabetic nephropathy, which contributes to the
early evaluation of diabetic kidney damage and has an important value for early detection.

      【Key words】 Urinary microalbumin; Diabetic nephropathy; Detection; Diagnosis
·论 著·doi:10.3969/j.issn.1003-6350.2013.13.0810