标题：妊娠期糖尿病的及时诊断和治疗对妊娠结局的影响

      作者：邹清如，黄利兰，宋 薇，黄国清，蔡芬兰
    (深圳市观澜人民医院妇产科，广东 深圳 518110)

      卷次： 2013年24卷13期

      【摘要】 目的 探讨妊娠期糖尿病的及时诊断和治疗对妊娠结局的影响。方法 选取我院诊治的60例妊
娠期糖尿病作为观察组，确诊后给予饮食、运动和药物治疗；选取同期120例正常妊娠孕妇作为对照组。观察妊
娠期糖尿病患者治疗前后血糖水平[空腹血糖(FPG)、餐后2h血糖(2hPG)、餐后最高血糖]，同时观察和比较两组孕
产妇的并发症（妊高征、羊水过多、胎膜早破、产后出血）、分娩方式（阴道分娩、剖宫产）、围生儿结局（早产、巨大
儿、新生儿窒息、新生儿呼吸窘迫综合征）。结果 与治疗前相比，妊娠期糖尿病患者治疗后FPG、2hPG、餐后最
高血糖水平均显著降低（P<0.05）；与对照组相比，观察组孕产妇在并发症、阴道分娩率、剖宫产率以及围生儿结
局等方面，差异均无统计学意义（P>0.05）。结论 妊娠期糖尿病患者若得到及时诊断和规范化治疗均能够达到
正常妊娠结局。

      【关键词】 妊娠期糖尿病；诊断；治疗；妊娠结局

      【中图分类号】 R714.255 【文献标识码】 A 【文章编号】 1003—6350（2013）13—1916—03


Effect of timely diagnosis and treatment of gestational diabetes mellitus on pregnancy outcome.
ZOU Qing-ru,
HUANG Li-lan, SONG Wei, HUANG Guo-qing, CAI Fen-lan. Department of Obstetrics and Gynecology, Guanlan
People's Hospital of Shenzhen City, Shenzhen 518110, Guangdong, CHINA

【Abstract】 Objective To study the effect of timely diagnosis and treatment of gestational diabetes mellitus
(GDM) on pregnancy outcome. Methods Sixty patients with GDM in our hospital were regarded as the observation
group, which were treated by diet, exercise and medication after diagnosis. One hundred and twenty normal pregnant
women in the same period were regarded as the control group. The blood glucose changes (fasting plasma glucose
FPG, 2-hour postprandial blood glucose 2hPG, and postprandial highest blood glucose) at the pre-treatment and
post-treatment for the patients with gestational diabetes were measured and compared. The maternal complications
such as pregnancy hypertension, polyhydramnios, premature rupture of membranes, and postpartum hemorrhage were
observed and compared. The delivery mode of vaginal delivery and cesarean section was observed and compared. The
perinatal child outcomes including preterm, huge children, neonatal asphyxia and neonatal respiratory distress syn-
drome were observed and compared. Results Compared with pre-treatment, the FPG, 2hPG and postprandial highest
blood glucose in GDM patients were obviously decreased, P<0.05. Compared with the control group, the incidence of
maternal complication, vaginal delivery and cesarean section, and perinatal child outcome in the observation group
were no significantly different, P>0.05. Conclusion For patients with gestational diabetes, timely diagnosis and stan-
dardized treatment can achieve normal pregnancy outcome.

      【Key words】 Gestational diabetes mellitus; Diagnosis; Treatment; Pregnancy outcome
·论 著·doi:10.3969/j.issn.1003-6350.2013.13.0794