标题：口腔护理干预对复发性肾病综合征咽部微生态的影响

      作者：谭宗凤，温向琼
    （泸州医学院附属医院肾病内科，四川 泸州 646000）

      卷次： 2013年24卷11期

      【摘要】 目的 探讨口腔护理干预对复发性肾病综合征咽部微生态的影响。方法 选择我科住院的肾病
综合征复发患者75例为复发组，另选健康人75例为正常对照组，两组进行咽部微生态比较，了解复发组主要的
致病菌；观察复发组通过口腔护理干预后致病菌的变化情况。结果 复发组白色念珠菌、乙型溶血性链菌的检
出率高于对照组。说明白色念珠菌、乙型溶血性链菌是复发组主要的致病菌。而复发组在行口腔护理一个疗程
后，白色念珠菌检出率为0% (P<0.01)，乙型溶血性链菌检出率为1.33% (P<0.05)，与口腔护理前相比，差别有统计
学意义。结论 口腔护理干预对肾病综合征复发患者咽部微生态的影响明显，不仅可以改善口腔健康状态，而
且为预防或减少肾病综合征的复发提供了理论依据。

      【关键词】 口腔护理；肾病综合征；复发；咽部；微生态

      【中图分类号】 R473.78 【文献标识码】 A 【文章编号】 1003—6350（2013）11—1712—03


Effect of oral nursing on pharyngeal microecology in patients with recurrent nephrotic syndrome.
TAN
Zong-feng, WEN Xiang-qiong. Department of Nephrology, the Affiliated Hospital of Luzhou Medical College, Luzhou
646000, Sichuan, CHINA

【Abstract】 Objective To investigate the effect of oral nursing on pharyngeal microecology in patients with
recurrent nephrotic syndrome. Methods Seventy-five inpatients with recurrent nephrotic syndrome in our hospital
were selected as the recurrent group, while 75 healthy volunteers were enrolled as the control group. In order to inves-
tigate the main pathogenic bacteria in the recurrent group, pharyngeal microecology among the recurrent group and
the control group were compared. After oral nursing, pharyngeal microecology was examined again in the recurrent
group. Results Compared with control group, Candida albicans and B chain bacteria were more common in the re-
current group, which suggested that Candida albicans and B chain bacteria were the main pathogenic bacteria for recur-
rence. After oral nursing, Candida albicans cann't be detected (P<0.001), while the detection rate of B chain bacteria
was 1.33% (P<0.005), which suggested that oral nursing may decrease pharyngeal pathogenic bacteria in recurrent
group. Conclusion Oral nursing may improve pharyngeal microecology and prevent disease recurrence in patients
with recurrent nephrotic syndrome.

      【Key words】 Oral nursing; Nephrotic syndrome; Recurrent; Pharyngeal; Microecology
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