标题：组织多普勒成像对妊娠糖尿病孕妇及胎儿心脏功能的研究

      作者：吴 玮，余 杨，李 瑛，丁琳灵，彭 波，蒋 明，刘惠莲，秦 岚
    （深圳市第七人民医院超声室，广东 深圳 518081）

      卷次： 2013年24卷7期

      【摘要】 目的 应用组织多普勒成像技术(DTI)检测妊娠糖尿病(GDM)孕妇与胎儿心脏功能状况，明确两者
间的相互作用，为临床处置提供必要依据。方法 对50例糖尿病组和50例正常对照组的孕妇及胎儿分别进行
常规心脏参数及房室瓣环平面四个位点的心肌运动速度的检测，了解其心脏功能状况，并分别进行统计学处
理。结果 糖尿病组孕妇及胎儿心肌厚度明显大于对照组(P<0.05)，心肌厚度增加在妊娠晚期(>33周)表现更为
明显；糖尿病组胎儿较对照组胎儿Sm、Em及Am均下降，其差异具有统计学意义(P<0.05)；而射血分数EF值均大
于对照组(P<0.05)。糖尿病组孕妇房室瓣环心肌运动速度Sm、Em均降低，Am升高与对照组相比，差异均具有统
计学意义(P<0.05)，其舒张功能Em值的降低与胎儿Em值降低呈正相关(r=0.79，P<0.05)，Am值的升高与胎儿Am
值升高呈正相关(r=0.77，P<0.05)。结论 组织多普勒成像能直接观察房室瓣环的运动，能精确地反映GDM孕妇
及胎儿心脏功能受损的状况。

      【关键词】 组织多普勒成像；房室瓣环平面；心脏功能；孕妇; 胎儿；妊娠糖尿病

      【中图分类号】 R714.256 【文献标识码】 A 【文章编号】 1003—6350(2013)07—0991—04


Evaluating cardiac function of pregnant women with gestational diabetes and fetuses by tissue Doppler
imaging.
WU Wei, YU Yang, LI Ying, DING Ling-ling, PENG Bo, JIANG Ming, LIU Hui-lian, QIN Lan. Department of
Ultrasound, the Seventh People’s Hospital of Shenzhen, Shenzhen 518081, Guangdong, CHINA

【Abstract】 Objective To evaluate the cardiac function of pregnant women with gestational diabetes and fe-
tuses by tissue Doppler imaging. Methods Routine cardiac parameters and myocardial motion velocities of four
sites of atrioventricular valve ring were detected in 50 pregnant women with gestational diabetes and their fetuses (the
diabetes group) as well as 50 healthy pregnant women and their fetuses (the control group) by tissue Doppler imaging.
Results The myocardial thickness of the women in the diabetes group was significantly larger than that in the con-
trol groups (P<0.05). The increase of myocardial thickness was extremely obvious in the late trimester of pregnan-
cy. The Sm, Em and Am of fetuses were significantly lower in the diabetes group than the control group, with statis-
tically significant difference (P<0.05), and the EF were significantly higher (P<0.05). The Sm and Em of myocardi-
al motion velocities were significantly lower in the diabetes group than the control group, and the Am were signifi-
cantly higher (P<0.05). The decrease of pregnant women had positive correlation with the decrease of the Em of fe-
tuses (r=0.79, P<0.05). The increase of Am of regnant women showed positive correlation with the increase of the Am
of fetuses (r=0.77, P<0.05). Conclusion Tissue Doppler imaging can reflect the cardiac function of the pregnant
women with gestational diabetes and their fetuses.

      【Key words】 Tissue Doppler imaging; Atrioventricular valve ring; Cardiac function; Pregnant women; Fetus-