标题：慢性甲苯中毒患者的脑电图分析

      作者：刘文萍 1，李爱红 1，王建如 2
    (西安医学院第二附属医院功能科 1、医学影像科 2，陕西 西安 710038)

      卷次： 2013年24卷6期

      【摘要】 目的 探讨慢性甲苯中毒对脑电活动的影响。方法 对48例慢性甲苯中毒患者进行脑电图（EEG）检
查，并随机选择48名正常人作为对照组，同时将慢性苯中毒患者分为不同工龄组进行分析对比。结果 慢性甲苯中
毒组EEG异常31例（64.6%），对照组8例（16.7%），慢性苯中毒组EEG异常率明显高于对照组(P＜0.01)，两组比
较差异有统计学意义，慢性苯中毒不同工龄组EEG比较差异无统计学意义。结论 苯的毒性作用对脑细胞的电
生理有一定影响，毒性作用并不随着工龄的上升而增加。EEG作为一种无创性电生理检查，可用于慢性甲苯中
毒的辅助诊断。

      【关键词】 慢性甲苯中毒；脑电图；甲苯

      【中图分类号】 R595.1 【文献标识码】 A 【文章编号】 1003—6350（2013）06—0849—02


Analysis of EEG in patients with benzene poisoning.
LIU Wen-ping 1, LI Ai-hong 1, WANG Jian-ru 2. Function
Examination Department 1, Medical Image Department 2, the Second Affiliated Hospital of Xi'an Medical College, Xi'an
710038, Shaanxi, CHINA

【Abstract】 Objective To investigate the effect of chronic benzolism on EEG activity. Methods For-
ty-eight patients with chronic benzolism were monitored by EEG, and 48 healthy controls were also examined. Pa-
tients with different lengths of service were analyzed simultaneously. Results EEG abnormality in patients with
chronic benzolism were 31 cases (64.6%), and 8 cases (16.7%) in controls. The abnormality in patients with chronic
benzolism were markedly higher than that in healthy controls (P＜0.01). The different seniority of chronic benzene
poisoning has no significant effect on EEG activity. Conclusion Benzene toxic effects on brain cell electrophysiolo-
gy had certain effect, but the toxic effects did not vary with the age increases. EEG, as a noninvasive electrophysilogi-
cal examination, can be used for the diagnosis of chronic toluene poisoning.