标题：SPECT/CT融合显像在骨转移瘤诊断中的应用价值

      作者：苏玉玲
    (暨南大学医学院附属珠海医院 珠海市人民医院核医学科，广东 珠海 519000)

      卷次： 2013年24卷6期

      【摘要】 目的 评价99mTc-MDP SPECT/CT融合显像在骨转移瘤诊断中的应用价值。方法 对临床已确
诊的55例恶性肿瘤患者，进行全身骨显像及局部SPECT/CT融合显像。结果 乳腺癌和肺癌以溶骨型骨转移为
主，前列腺癌以成骨型骨转移为主。乳腺癌以胸部、脊柱和骨盆转移为主，在22例胸部骨转移中，包含10例肋骨
和12例胸骨转移，且均以溶骨型转移为主；肺癌和前列腺癌骨转移以脊柱和骨盆为主。79处病灶行SPECT/CT
融合显像，最终诊断为 17处良性病变，62处恶性病变；SPECT、SPECT/CT对病灶诊断的灵敏度分别为 96.8%、
98.4%，特异性分别为82.4%、100%，准确性分别为93.7%、98.7%。结论 SPECT/CT融合显像在骨转移瘤诊断中
具有良好的临床应用价值。

      【关键词】 SPECT/CT；放射性核素显像；骨转移；图像融合

      【中图分类号】 R738.1 【文献标识码】 A 【文章编号】 1003—6350（2013）06—0842—03


Application of SPECT/CT fusion imaging in the diagnosis of bone metastasis.
SU Yu-ling. Department of Nuclear
Medicine, People's Hospital of Zhuhai (Zhuhai Hospital Affiliated to School of Medicine, Jinan University), Zhuhai
519000, Guangdong, CHINA

【Abstract】 Objective To evaluate the value of the single photon emission computed tomography-computed
tomography (SPECT/CT) fusion imaging in the diagnosis of bone metastasis. Methods Fifty-five cancer patients un-
derwent whole-body bone scan and SPECT/CT fusion imaging. Results Breast cancer and lung cancer were mainly
osteolytic metastasis, prestate cancer was sclerotic metastasis. Chest, vertebral column and pelvis were the most com-
mon sites of breast cancer metastasis. There were 22 cases of chest metastasis, including 12 cases of sternal and 14 cas-
es of ribs metastasis, mainly osteolytic metastasis. The vertebral column and pelvis were the most common sites of me-
tastasis of lung and prestate cancers. Seventy-nine lesions were detected in SPECT/CT, including 17 benign lesions
and 62 malignant lesions. The diagnostic sensitivity of SPECT and SPECT/CT was 96.8% and 98.4%, respectively.
The specificity of two types of imaging was 82.4% and 100%, respectively, and the accuracy was 93.7% and 98.7%,
respectively. Conclusion SPECT/CT had an important value in the diagnosis of bone metastasis.

      【Key words】 SPECT/CT; Radionuclide imaging; Bone metastasis; Fusion imaging