标题：参麦对早期宫颈癌术后放疗患者免疫功能的影响

      作者：周艳芳，杨心凤
    （江西省肿瘤医院，江西 南昌 330029）

      卷次： 2013年24卷4期

      【摘要】 目的 探讨手术联合放疗对早期宫颈癌患者的临床疗效，评价参麦注射液对患者免疫功能的影响。
方法 选择我院收治的68例早期宫颈癌患者，根据治疗方式不同分为观察组和对照组，两组患者均给予放疗联
合广泛性子宫切除+盆腔淋巴结清扫术，观察组另外给予参麦注射液治疗，比较并分析两组患者的疗效及治疗前
后的免疫功能。结果 观察组治疗有效率为 79.4%，对照组为 70.6%，两组比较差异无统计学意义(P>0.05)。
对照组治疗后的CD3+、CD8+及NK细胞水平显著低于治疗前(P<0.05)，也低于观察组治疗后的免疫功能指标
(P<0.05)。结论 手术联合放疗治疗早期宫颈癌疗效显著，参麦注射液对细胞免疫功能有一定的恢复作用。

      【关键词】 局部；宫颈癌；免疫功能

      【中图分类号】 R73 【文献标识码】 A 【文章编号】 1003—6350（2013）04—0489—02


Effect of shenmai injection on the immune function in patients with postoperative radiotherapy for cervical
cancer.
ZHOU Yan-fang, YANG Xin-feng. The Tumor Hospital of Jiangxi Province, Nanchang 330029, Jiangxi, CHINA

【Abstract】 Objective To investigate the clinical effect of surgery combined with radiotherapy for treating cer-
vical cancer, and to evaluate the influence of shenmai injection on the immune function of the patients. Methods Six-
ty-eight patients with early cervical cancer was selected and divided into the observation group and control group. All
the patients were given chemotherapy combined with hysterectomy and pelvic lymph node dissection. Patients in the
observation group were additionally treated by shenmai injection. The clinical effect and immune function were com-
pared between the two groups. Results The effective rate was 79.4% in the observation group and 70.6% in the con-
trol group, with no statistically significant difference between the two groups (P>0.05). The levels of CD3 +, CD8 + and
NK cells after treatment in the control group were significantly lower than those before treatment (P<0.05), which
were also significantly lower than the levels in the observation group (P<0.05). Conclusion Surgery combined radio-
therapy has significant clinical effect in the treatment of cervical cancer. Shenmai injection has certain recovery effect
on cellular immune function.