首页 > 期刊检索 > 详细
      标题:异位妊娠药物保守治疗效果及其影响因素分析
      作者:李婵娟,凌 斌
    (安徽医科大学妇产科,安徽 合肥 230032)
      卷次: 2013年24卷4期
      【摘要】 目的 分析影响异位妊娠药物保守治疗效果的因素。方法 对我院妇产科2008年6月至2011年6月
收治的100例异位妊娠患者进行药物保守治疗,将所有患者根据药物治疗是否成功分为成功组与失败组,比较两组
患者的停经时间、腹痛天数、血HCG水平、血孕酮水平、彩超结果,并用Logistic回归分析影响异位妊娠药物治疗成
功率的因素。结果 单因素分析显示,停经时间、血HCG水平、血孕酮水平、彩超显示包块大小影响药物保守治疗的
成功率,停经时间越短、血HCG水平与孕酮水平越低,包块直径越小成功率越高(P<0.05);腹痛时间、盆腔积液量对
药物治疗成功率影响不明显(P>0.05)。Logistic多因素分析显示,血HCG水平、包块大小是影响药物保守治疗成功
率的因素。结论 患者血HCG水平、停经天数、包块大小是影响药物保守治疗成功与否的关键因素,停经时间也是
因素之一,治疗时应根据患者临床表现及辅助检查结果选择治疗方案,提高成功率,以免给患者造成不必要的负担。

      【关键词】 异位妊娠;药物保守治疗;效果;影响因素

      【中图分类号】 R714.22 【文献标识码】 A 【文章编号】 1003—6350(2013)04—0501—03

Clinical effect of conservative drug treatment for ectopic pregnancy and the influencing factors. LI Chan-juan,
LING Bing. Department of Gynaecology and Obstetrics, Anhui Medical University, Hefei 230032, Anhui, CHINA

      【Abstract】 Objective To analyze the factors influencing the clinical effect of conservative drug treatment
for ectopic pregnancy. Methods One hundred patients with ectopic pregnancy admitted in our hospital from June,
2008 to June, 2011 received conservative drug treatment, which were divided into the success group and the fail group
according to the outcome of treatment. The days of amenorrhea, days of pain, levels of human chorionic gonadotrophin
(HCG) and blood progesterone, as well as the sonographic results were compared between the two groups. The factors in-
fluencing the clinical effect of the treatment were analyzed by logistic regression analysis. Results Single factor analysis
showed that days of amenorrhea, HCG level, mass diameter, progesterone level were the factors that influence the outcome
of the treatment. The success of the treatment was correlated with shorter amenorrhea time, lower levels of HCG and pro-
gesterone, and smaller mass diameter (P<0.05), but not with the duration of abdominal pain and the amount of pelvic hy-
drocele (P>0.05). Multiple factor analysis showed that HCG levels, mass diameter and days of amenorrhea were indepen-
dent factors that influence the therapeutic effect. Conclusion HCG level, mass diameter and days of amenorrhea are inde-
pendent factors that influence the therapeutic effect of conservative drug treatment. We should choose treatment protocols
based on the clinical manifestations and auxiliary examination, in order to improve the success rate of treatment.

      【Key words】 Ectopic pregnancy; Conservative drug treatment; Effect; Influence factor

       下载PDF